CYTH proteins stimulate ARF1 GTPase activity

Stable Identifier
R-HSA-8847883
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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CYTH proteins stimulate the GTPase activity of ARF1, promoting the exchange of GTP for GDP and thereby inactivating ARF1 (Franco et al, 1998; Drin et al, 2008; reviewed in Jackson and Casanova, 2000).

Literature References
PubMed ID Title Journal Year
18451304 Asymmetric tethering of flat and curved lipid membranes by a golgin

Drin, G, Morello, V, Casella, JF, Gounon, P, Antonny, B

Science 2008
10652516 Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factors

Jackson, CL, Casanova, JE

Trends Cell Biol. 2000
9707577 ARNO3, a Sec7-domain guanine nucleotide exchange factor for ADP ribosylation factor 1, is involved in the control of Golgi structure and function

Franco, M, Boretto, J, Robineau, S, Monier, S, Goud, B, Chardin, P, Chavrier, P

Proc. Natl. Acad. Sci. U.S.A. 1998
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
GTPase activity of ARF1:GTP:CYTH1,2,3,4 [Golgi membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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