Reactome | CYTH1 [Golgi membrane]

CYTH1 [Golgi membrane]

Stable Identifier

R-HSA-8847825

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15438 CYTH1

Gene Names

CYTH1, D17S811E, PSCD1

Chain

chain:1-398

Reference Genes

BioGPS Gene:9267 CYTH1

COSMIC (genes):CYTH1 CYTH1

CTD Gene:9267 CYTH1

dbSNP Gene:9267 CYTH1

ENSEMBL:ENSG00000108669 CYTH1

HGNC:9501 CYTH1

Monarch:9267 CYTH1

NCBI Gene:9267 CYTH1

OMIM:182115 CYTH1

UCSC:Q15438 CYTH1

Reference Transcript

Other Identifiers

11744293_a_at

11749337_a_at

11754351_a_at

16849501

202879_PM_s_at

202879_s_at

202880_PM_s_at

202880_s_at

3772526

3772527

3772528

3772529

3772530

3772531

3772532

3772533

3772534

3772535

3772540

3772541

3772542

3772543

3772547

3772549

3772551

3772552

3772553

3772554

3772555

3772556

3772557

3772558

3772560

3772561

3772564

3772565

3772569

3772580

38666_at

8018922

9267

A_23_P83781

A_33_P3332744

A_33_P3380405

GE80345

GO:0000139

GO:0005085

GO:0005515

GO:0005737

GO:0005829

GO:0005886

GO:0005912

GO:0005923

GO:0007163

GO:0008289

GO:0009898

GO:0016192

GO:0030155

GO:0032012

GO:0090162

GO:0098772

HMNXSV003000455

HMNXSV003019778

Hs.1050.0.S1_3p_a_at

ILMN_1694084

ILMN_2403852

M85169_at

PH_hs_0000137

TC17001920.hg

g4758963_3p_a_at

Participates

as a member of

CYTH1,2,3,4 [Golgi membrane] (Homo sapiens)

Other forms of this molecule

CYTH1 [cytosol]

Inferred To

SEC7 [Golgi membrane] (Saccharomyces cerevisiae)

step [Golgi membrane] (Drosophila melanogaster)

sec71 [Golgi membrane] (Schizosaccharomyces pombe)

sec72 [Golgi membrane] (Schizosaccharomyces pombe)

cyth2 [Golgi membrane] (Xenopus tropicalis)

CYTH1 [Golgi membrane] (Bos taurus)

CYTH1 [Golgi membrane] (Canis familiaris)

CYTH1 [Golgi membrane] (Dictyostelium discoideum)

CYTH1 [Golgi membrane] (Gallus gallus)

CYTH1 [Golgi membrane] (Mus musculus)

CYTH1 [Golgi membrane] (Rattus norvegicus)

CYTH1 [Golgi membrane] (Sus scrofa)

Homologues of CYTH1 [Golgi membrane] (Dictyostelium discoideum)

Homologues of CYTH1 [Golgi membrane] (Schizosaccharomyces pombe)

Cross References

ENSEMBL

ENST00000589297, ENSP00000466512, ENST00000591455, ENST00000585509, ENSP00000465940, ENSP00000465665, ENST00000446868, ENSP00000389095

OpenTargets

ENSG00000108669

HPA

ENSG00000108669-CYTH1

PRO

Q15438

Pharos - Targets

Q15438

HMDB Protein

HMDBP08338

PDB

4A4P, 1BC9

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P07900 HSP90AA1	8	HSP90AA1 [lysosomal lumen] (R-HSA-9622850) HSP90AA1 [cytosol] (R-HSA-192864) HSP90AA1 [nucleoplasm] (R-HSA-5082401) HSP90AA1 [plasma membrane] (R-HSA-534996) HSP90AA1 [secretory granule lumen] (R-HSA-6801515) HSP90AA1 [extracellular region] (R-HSA-3221946) HSP90AA1 [ficolin-1-rich granule lumen] (R-HSA-6801470) HSP90AA1 [endocytic vesicle lumen] (R-HSA-3221912)	0.556	3
UniProt:Q9UNE7 STUB1	1	STUB1 [cytosol] (R-HSA-975970)	0.556	3
UniProt:P31749 AKT1	14	p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-S473-AKT1 [plasma membrane] (R-HSA-377265) AKT1 [plasma membrane] (R-HSA-199416) AKT1 [cytosol] (R-HSA-58252) p-T308-AKT1 [cytosol] (R-HSA-198634) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-S473-AKT1 [cytosol] (R-HSA-9841264) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [cytosol] (R-HSA-2219526) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994)	0.556	3

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