Reactome | DSG4 [cornified envelope]

DSG4

Stable Identifier

R-HSA-8847713

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cornified envelope

Synonyms

Desmoglein-4, DSG4_HUMAN

Locations in the PathwayBrowser

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Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of the cornified envelope (Homo sapiens)
    - Plasma membrane resorption (Homo sapiens)
      - Mature cornified envelope [cornified envelope] (Homo sapiens)
        
        No FGN-cornified envelope:CDSN [cornified envelope] (Homo sapiens)
        
        No FGN-Cornified envelope [cornified envelope] (Homo sapiens)
        
        No FGN-early cornified envelope [cornified envelope] (Homo sapiens)
        
        Keratin tonofilament:Desmosome network [cornified envelope] (Homo sapiens)
        
        Keratin tonofilament:Desmosome [cornified envelope] (Homo sapiens)
        
        Desmosome [cornified envelope] (Homo sapiens)
        
        Desmogelins [cornified envelope] (Homo sapiens)
        
        DSG4 [cornified envelope] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q86SJ6 DSG4

Gene Names

DSG4, CDHF13

Chain

signal peptide:1-23, propeptide:24-49, chain:50-1040

Reference Genes

BioGPS Gene:147409 DSG4

COSMIC (genes):DSG4 DSG4

CTD Gene:147409 DSG4

dbSNP Gene:147409 DSG4

ENSEMBL:ENSG00000175065 DSG4

HGNC:21307 DSG4

KEGG Gene (Homo sapiens):hsa:147409 DSG4

Monarch:147409 DSG4

NCBI Gene:147409 DSG4

OMIM:607892 DSG4

UCSC:Q86SJ6 DSG4

Reference Transcript

Other Identifiers

0000780278

11734630_a_at

147409

1561330_at

16851727

3783436

3783437

3783438

3783444

3783445

3783446

3783447

3783448

3783449

3783450

3783453

3783456

3783457

3783458

3783459

3783460

3783461

3783462

3783463

3783464

3783465

3783466

3783467

59456

8020740

A_14_P133918

A_32_P538928

AAH39098

AAI32908

AAI32910

AAO43657

AAO47077

AAO47078

AAP45000

AAP49811

AY168788

AY177663

AY177664

AY227350

AY228236

BC039098

BC132907

BC132909

CCDS11897

CCDS45845

DSG4

DSG4-201

DSG4-202

ENSG00000175065

ENSP00000311859

ENSP00000352785

ENST00000308128

ENST00000359747

EntrezGene:147409

GE746997

GO:0001533

GO:0001942

GO:0003674

GO:0005509

GO:0005575

GO:0005623

GO:0005886

GO:0007155

GO:0007156

GO:0007165

GO:0008150

GO:0008219

GO:0009058

GO:0016020

GO:0016021

GO:0030054

GO:0030057

GO:0030154

GO:0030216

GO:0030509

GO:0031424

GO:0034641

GO:0043167

GO:0046872

GO:0048856

GO:0070268

GO:0098609

HGNC:21307

HPA059456

Hs2.407618.1.S1_3p_at

ILMN_1812799

IPR000233

IPR002126

IPR009122

IPR009123

IPR015919

IPR020894

IPR027397

MIM:607892

MIM:607903

NM_001134453

NM_177986

NP_001127925

NP_817123

PF00028

PF01049

PH_hs_0019428

PR00205

PR01818

PR01819

SM00112

TC18000125.hg

uc002kwq.3

uc002kwr.3

UPI0000062276

UPI000035DB4E

Participant Of

hasMember

Desmogelins [cornified envelope]

Other forms of this molecule

DSG4 [plasma membrane]

Inferred To

DSG4 [cornified envelope] (Bos taurus)

DSG4 [cornified envelope] (Canis familiaris)

DSG4 [cornified envelope] (Mus musculus)

DSG4 [cornified envelope] (Rattus norvegicus)

DSG4 [cornified envelope] (Sus scrofa)

Cross References

RefSeq

NP_001127925.1, NP_817123.1

GeneCards

Q86SJ6

PRO

Q86SJ6

Orphanet

17330

HMDB Protein

HMDBP07661