Reactome | DSG4 [cornified envelope]

DSG4 [cornified envelope]

Stable Identifier

R-HSA-8847713

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cornified envelope

Synonyms

Desmoglein-4, DSG4_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of the cornified envelope (Homo sapiens)
    - Plasma membrane resorption (Homo sapiens)
      - Mature cornified envelope [cornified envelope] (Homo sapiens)
        
        No FGN-cornified envelope:CDSN [cornified envelope] (Homo sapiens)
        
        No FGN-Cornified envelope [cornified envelope] (Homo sapiens)
        
        No FGN-early cornified envelope [cornified envelope] (Homo sapiens)
        
        Keratin tonofilament:Desmosome network [cornified envelope] (Homo sapiens)
        
        Keratin tonofilament:Desmosome [cornified envelope] (Homo sapiens)
        
        Desmosome [cornified envelope] (Homo sapiens)
        
        Desmogelins [cornified envelope] (Homo sapiens)
        
        DSG4 [cornified envelope] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q86SJ6 DSG4

Gene Names

DSG4, CDHF13

Chain

signal peptide:1-23, propeptide:24-49, chain:50-1040

Reference Genes

BioGPS Gene:147409 DSG4

COSMIC (genes):DSG4 DSG4

CTD Gene:147409 DSG4

dbSNP Gene:147409 DSG4

ENSEMBL:ENSG00000175065 DSG4

HGNC:21307 DSG4

KEGG Gene (Homo sapiens):147409 DSG4

Monarch:147409 DSG4

NCBI Gene:147409 DSG4

OMIM:607892 DSG4

UCSC:Q86SJ6 DSG4

Reference Transcript

Other Identifiers

0000780278

11734630_a_at

147409

1561330_at

16851727

3783436

3783437

3783438

3783444

3783445

3783446

3783447

3783448

3783449

3783450

3783453

3783456

3783457

3783458

3783459

3783460

3783461

3783462

3783463

3783464

3783465

3783466

3783467

3783469

8020740

A_14_P133918

A_32_P538928

GE746997

GO:0001533

GO:0001942

GO:0003674

GO:0005509

GO:0005575

GO:0005886

GO:0005911

GO:0007155

GO:0007156

GO:0007165

GO:0008150

GO:0008219

GO:0009058

GO:0016020

GO:0016021

GO:0030054

GO:0030057

GO:0030154

GO:0030216

GO:0030509

GO:0031424

GO:0034641

GO:0043167

GO:0046872

GO:0048856

GO:0070268

GO:0098609

Hs2.407618.1.S1_3p_at

ILMN_1812799

PH_hs_0019428

TC18000125.hg

Participant Of

hasMember

Desmogelins [cornified envelope]

Other forms of this molecule

DSG4 [plasma membrane]

Inferred To

DSG4 [cornified envelope] (Sus scrofa)

Dsg4 [cornified envelope] (Mus musculus)

Cross References

RefSeq

NP_001127925.1, NP_817123.1

OpenTargets

ENSG00000175065

GeneCards

Q86SJ6

HPA

ENSG00000175065-DSG4

Ensembl

ENST00000359747, ENST00000308128, ENSP00000311859, ENSP00000352785, ENSG00000175065

PRO

Q86SJ6

Orphanet

17330

HMDB Protein

HMDBP07661

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