SLCO3A1 isoform 1 has abroad substrate specificity

Stable Identifier
R-HSA-879584
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The human gene SLCO3A1 encodes the organic anion transporting polypeptide D. Several variants are expressed but isoform 1 is ubiquitous and can transport a range of substrates including the prostaglandins E1 and E2, thyroxine and vasopressin (AVP) (Huber RD et al, 2007).

Literature References
PubMed ID Title Journal Year
16971491 Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain

Huber, RD, Gao, B, Sidler Pfändler, MA, Zhang-Fu, W, Leuthold, S, Hagenbuch, B, Folkers, G, Meier, PJ, Stieger, B

Am J Physiol Cell Physiol 2007
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
sodium-independent organic anion transmembrane transporter activity of SLCO3A1-1 [plasma membrane]
Physical Entity
Activity
Orthologous Events
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Reviewed
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