Bcl-2 and Bcl-XL bind NLRP1

Stable Identifier
R-HSA-879201
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The anti-apoptotic proteins Bcl-2 and Bcl-XL (but not Mcl-1, Bcl-W, Bfl-1 or Bcl-B) bind to NLRP1, preventing MDP-induced activation.

Literature References
PubMed ID Title Journal Year
17418785 Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

Bruey, JM, Bruey-Sedano, N, Luciano, F, Zhai, D, Balpai, R, Xu, C, Kress, CL, Bailly-Maitre, B, Li, X, Osterman, A, Matsuzawa, S, Terskikh, AV, Faustin, B, Reed, JC

Cell 2007
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created