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IFNA10 [extracellular region]
Stable Identifier
R-HSA-877339
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Interferon alpha-10, IFN10_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Factors involved in megakaryocyte development and platelet production (Homo sapiens)
Expression of Interferon-alpha and beta (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Activation of JAK kinases (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Formation of p-STAT1 homodimer (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFN alpha/beta binds to IFNAR2 (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Phosphorylation of INFAR1 by TYK2 (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Phosphorylation of STAT1 (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Phosphorylation of STAT2 (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Recruitment of IFNAR1 (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Recruitment of STAT2 to p-IFNAR1 (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Regulation of IFNA signaling (Homo sapiens)
Dephosphorylation of JAK1 by SHP1 (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Dephosphorylation of STAT1 by SHP2 (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Dephosphorylation of TYK2 by PTP1B (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Inhibition of JAK kinase activity by SOCS1/3 (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Release of p-STAT2:p-STAT1 dimer (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
Innate Immune System (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
TRAF6 mediated IRF7 activation (Homo sapiens)
Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 (Homo sapiens)
IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
IFNA [extracellular region] (Homo sapiens)
IFNA10 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01566 IFNA10
Gene Names
IFNA10
Chain
signal peptide:1-23, chain:24-189
Reference Genes
BioGPS Gene:3446 IFNA10
COSMIC (genes):IFNA10 IFNA10
CTD Gene:3446 IFNA10
dbSNP Gene:3446 IFNA10
ENSEMBL:ENSG00000186803 IFNA10
HGNC:5418 IFNA10
KEGG Gene (Homo sapiens):3446 IFNA10
Monarch:3446 IFNA10
NCBI Gene:3446 IFNA10
OMIM:147577 IFNA10
UCSC:P01566 IFNA10
Reference Transcript
RefSeq:NM_002171.2 IFNA10
Other Identifiers
0000450463
11715139_x_at
11741919_x_at
1580_f_at
17092831
207964_3p_x_at
207964_x_at
208261_3p_x_at
208261_x_at
211405_3p_x_at
211405_x_at
3201182
3201183
3201189
3201190
3201192
3201193
3201226
3201227
3201228
3201229
3201230
3201231
3201232
3201233
3201241
3201243
3201245
3201246
3201247
3201302
3446
427_f_at
8160377
8160389
8160394
A_23_P20704
GE570550
GO:0002250
GO:0002286
GO:0002323
GO:0002376
GO:0003674
GO:0005125
GO:0005126
GO:0005132
GO:0005575
GO:0005576
GO:0005615
GO:0006464
GO:0006950
GO:0006952
GO:0006959
GO:0007165
GO:0007596
GO:0008150
GO:0008283
GO:0019221
GO:0030154
GO:0030183
GO:0033141
GO:0042100
GO:0043330
GO:0048856
GO:0051607
GO:0060337
ILMN_1769988
J00209_f_at
M27318_f_at
PH_hs_0032473
TC09000952.hg
V00551_f_at
g10800141_3p_s_at
g184598_3p_s_at
g186407_3p_s_at
g4504588_3p_at
g4504588_3p_x_at
Participant Of
hasMember
IFNA [extracellular region]
Inferred To
Homologues of IFNA1 [extracellular region] (Bos taurus)
Homologues of IFNA1 [extracellular region] (Danio rerio)
Homologues of IFNA1 [extracellular region] (Gallus gallus)
Homologues of IFNA1 [extracellular region] (Mus musculus)
Homologues of IFNA1 [extracellular region] (Rattus norvegicus)
Homologues of IFNA1 [extracellular region] (Sus scrofa)
Homologues of IFNA1 [extracellular region] (Xenopus tropicalis)
Ifna14 [extracellular region] (Mus musculus)
Ifna12 [extracellular region] (Mus musculus)
IFNAG [extracellular region] (Bos taurus)
LOC618947 [extracellular region] (Bos taurus)
ifn3 [extracellular region] (Xenopus tropicalis)
ifnphi3 [extracellular region] (Danio rerio)
Ifna16 [extracellular region] (Mus musculus)
ifnphi1 [extracellular region] (Danio rerio)
Ifna1 [extracellular region] (Mus musculus)
Ifna1 [extracellular region] (Rattus norvegicus)
LOC100858762 [extracellular region] (Gallus gallus)
IFNKL1 [extracellular region] (Gallus gallus)
Ifna7 [extracellular region] (Mus musculus)
Ifna5 [extracellular region] (Mus musculus)
Ifna5 [extracellular region] (Rattus norvegicus)
IFNA1 [extracellular region] (Bos taurus)
IFNA1 [extracellular region] (Rattus norvegicus)
IFNA1 [extracellular region] (Sus scrofa)
IFNA1 [extracellular region] (Xenopus tropicalis)
ifn5 [extracellular region] (Xenopus tropicalis)
ifnphi4 [extracellular region] (Danio rerio)
IFNA [extracellular region] (Gallus gallus)
LOC100859414 [extracellular region] (Gallus gallus)
LOC523244 [extracellular region] (Bos taurus)
rac2 [extracellular region] (Xenopus tropicalis)
IFN-alpha-11 [extracellular region] (Sus scrofa)
Ifnab [extracellular region] (Mus musculus)
Ifna13 [extracellular region] (Mus musculus)
Ifna15 [extracellular region] (Mus musculus)
IFNAD [extracellular region] (Bos taurus)
LOC776018 [extracellular region] (Gallus gallus)
Ifna11 [extracellular region] (Mus musculus)
ifnphi2 [extracellular region] (Danio rerio)
Ifna9 [extracellular region] (Mus musculus)
Ifna4 [extracellular region] (Mus musculus)
Ifna4 [extracellular region] (Rattus norvegicus)
RGD1560539 [extracellular region] (Rattus norvegicus)
ifn2 [extracellular region] (Xenopus tropicalis)
Ifna16l1 [extracellular region] (Rattus norvegicus)
Ifna2 [extracellular region] (Mus musculus)
Ifna2 [extracellular region] (Rattus norvegicus)
LOC768614 [extracellular region] (Gallus gallus)
IFNA2 [extracellular region] (Gallus gallus)
Ifna6 [extracellular region] (Mus musculus)
IFNB [extracellular region] (Gallus gallus)
LOC100912314 [extracellular region] (Rattus norvegicus)
LOC100912356 [extracellular region] (Rattus norvegicus)
Cross References
RefSeq
NP_002162.1
OpenTargets
ENSG00000186803
GeneCards
P01566
HPA
ENSG00000186803-IFNA10
Ensembl
ENSG00000186803
,
ENSP00000369566
,
ENST00000357374
PRO
P01566
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