Reactome | IFNAR1 [plasma membrane]

IFNAR1 [plasma membrane]

Stable Identifier

R-HSA-877334

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Interferon alpha/beta receptor 1, INAR1_HUMAN

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External Reference Information

External Reference

UniProt:P17181 IFNAR1

Gene Names

IFNAR1, IFNAR

Chain

signal peptide:1-27, chain:28-557

Reference Genes

BioGPS Gene:3454 IFNAR1

COSMIC (genes):IFNAR1 IFNAR1

CTD Gene:3454 IFNAR1

dbSNP Gene:3454 IFNAR1

ENSEMBL:ENSG00000142166 IFNAR1

HGNC:5432 IFNAR1

KEGG Gene (Homo sapiens):3454 IFNAR1

Monarch:3454 IFNAR1

NCBI Gene:3454 IFNAR1

OMIM:107450 IFNAR1

UCSC:P17181 IFNAR1

Reference Transcript

Other Identifiers

0006760722

1157_s_at

11723423_x_at

11723424_at

11723425_at

11748615_a_at

16922260

18015

204191_at

225661_at

225669_at

29226

3454

3918575

3918576

3918582

3918583

3918584

3918585

3918586

3918588

3918590

3918592

3918595

3918597

3918599

3918600

3918601

3918602

3918603

3918604

3918605

3918606

3918607

3918608

3918609

3S98

3SE3

3SE4

48583_at

4PO6

8068266

A0A494BZU5

A0A494C0E2

A0A494C0K3

A0A494C0P2

A_33_P3277988

AAA52730

AAH02590

AAH21825

AAT49100

AF039907

AK222770

AK222812

AK298051

AK312631

AP000296

AP000297

AP000298

AY654286

BAD96490

BAD96532

BAG35516

BAG60345

BC002590

BC021825

C9J114

CAA42992

CCDS13624

CH471079

EAX09837

EAX09839

ENSG00000142166

ENSP00000270139

ENSP00000498654

ENST00000270139

ENST00000270139.7

ENST00000652450

EntrezGene:3454

EntrezGene:IFNAR1

g10835182_3p_at

GE57477

GE86827

GO:0002376

GO:0003674

GO:0004896

GO:0004904

GO:0004905

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005764

GO:0005768

GO:0005770

GO:0005773

GO:0005886

GO:0005887

GO:0006950

GO:0007165

GO:0007259

GO:0008150

GO:0009615

GO:0016020

GO:0016021

GO:0019221

GO:0019962

GO:0031410

GO:0032496

GO:0035457

GO:0043226

GO:0060337

HGNC:5432

HPA018015

HPA029226

Hs.181315.0.A1_3p_at

Hs.181315.0.A2_3p_at

IFNAR1

IFNAR1-201

IFNAR1-204

ILMN_1752923

IPR003961

IPR013783

IPR015373

IPR016669

IPR036116

J03171

J03171_at

MIM:107450

NM_000629

NP_000620

PF01108

PF09294

PH_hs_0008658

PH_hs_0022865

TC21000128.hg

UPI000006FE3C

UPI00017A79D5

X60459

XM_005260964

XP_005261021

Participant Of

hasComponent

Other forms of this molecule

p-Y466,Y481-IFNAR1 [plasma membrane]

Inferred To

crfb1 [plasma membrane] (Danio rerio)

ifngr1 [plasma membrane] (Danio rerio)

ifngr2.2 [plasma membrane] (Xenopus tropicalis)

il10rb [plasma membrane] (Danio rerio)

ifngr1l [plasma membrane] (Danio rerio)

Ifnar1 [plasma membrane] (Mus musculus)

Ifnar1 [plasma membrane] (Rattus norvegicus)

LOC609830 [plasma membrane] (Canis familiaris)

crfb4 [plasma membrane] (Danio rerio)

Homologues of IFNAR1 [plasma membrane] (Danio rerio)

Homologues of IFNAR1 [plasma membrane] (Xenopus tropicalis)

IFNAR1 [plasma membrane] (Bos taurus)

IFNAR1 [plasma membrane] (Danio rerio)

IFNAR1 [plasma membrane] (Gallus gallus)

IFNAR1 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_005261021.1, NP_000620.2

OpenTargets

ENSG00000142166

HPA

ENSG00000142166-IFNAR1

GeneCards

P17181

ZINC - Substances

INAR1_HUMAN

Ensembl

ENSP00000270139, ENSG00000142166, ENSP00000498654, ENST00000270139, ENST00000652450

ZINC target

P17181

PRO

P17181

ZINC - Predictions - Purchasable

INAR1_HUMAN

PDB

4PO6, 3SE4, 3S98, 3SE3

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P52630 STAT2	4	STAT2 [cytosol] (R-HSA-882029) p-Y-STAT2 [cytosol] (R-HSA-8987235) p-Y690-STAT2 [cytosol] (R-HSA-909683) p-Y690-STAT2 [nucleoplasm] (R-HSA-909673)	0.758	5
UniProt:P42224 STAT1	7	p-STAT1 [cytosol] (R-HSA-8950418) p-STAT1 [nucleoplasm] (R-HSA-8987140) p-Y701-STAT1 [nucleoplasm] (R-HSA-8985905) p-Y701-STAT1 [cytosol] (R-HSA-8951202) STAT1 [cytosol] (R-HSA-629622) p-Y701-STAT1 [cytosol] (R-HSA-3132766) p-Y701-STAT1 [nucleoplasm] (R-HSA-6788624)	0.499	2