Reactome | IFNAR1 [plasma membrane]

IFNAR1 [plasma membrane]

Stable Identifier

R-HSA-877334

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Interferon alpha/beta receptor 1, INAR1_HUMAN

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External Reference Information

External Reference

UniProt:P17181 IFNAR1

Gene Names

IFNAR1, IFNAR

Chain

signal peptide:1-27, chain:28-557

Reference Genes

BioGPS Gene:3454 IFNAR1

COSMIC (genes):IFNAR1 IFNAR1

CTD Gene:3454 IFNAR1

dbSNP Gene:3454 IFNAR1

ENSEMBL:ENSG00000142166 IFNAR1

HGNC:5432 IFNAR1

KEGG Gene (Homo sapiens):3454 IFNAR1

Monarch:3454 IFNAR1

NCBI Gene:3454 IFNAR1

OMIM:107450 IFNAR1

UCSC:P17181 IFNAR1

Reference Transcript

Other Identifiers

0006760722

1157_s_at

11723423_x_at

11723424_at

11723425_at

11748615_a_at

16922260

204191_at

225661_at

225669_at

3454

3918575

3918576

3918582

3918583

3918584

3918585

3918586

3918588

3918590

3918592

3918595

3918597

3918599

3918600

3918601

3918602

3918603

3918604

3918605

3918606

3918607

3918608

3918609

48583_at

8068266

A_33_P3277988

GE57477

GE86827

GO:0002376

GO:0003674

GO:0004896

GO:0004904

GO:0004905

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005764

GO:0005768

GO:0005770

GO:0005773

GO:0005886

GO:0005887

GO:0006950

GO:0007165

GO:0007259

GO:0008150

GO:0009615

GO:0016020

GO:0016021

GO:0019221

GO:0019962

GO:0031410

GO:0032496

GO:0035457

GO:0043226

GO:0060337

HMNXSV003051822

Hs.181315.0.A1_3p_at

Hs.181315.0.A2_3p_at

ILMN_1752923

J03171_at

PH_hs_0008658

PH_hs_0022865

TC21000128.hg

g10835182_3p_at

Participates

as a component of

Other forms of this molecule

p-Y466,Y481-IFNAR1 [plasma membrane]

Inferred To

il10rb [plasma membrane] (Danio rerio)

ifngr1l [plasma membrane] (Danio rerio)

Ifnar1 [plasma membrane] (Mus musculus)

Ifnar1 [plasma membrane] (Rattus norvegicus)

crfb4 [plasma membrane] (Danio rerio)

Homologues of IFNAR1 [plasma membrane] (Danio rerio)

IFNAR1 [plasma membrane] (Bos taurus)

IFNAR1 [plasma membrane] (Canis familiaris)

IFNAR1 [plasma membrane] (Gallus gallus)

Cross References

RefSeq

NP_000620.2, XP_005261021.1

OpenTargets

ENSG00000142166

GeneCards

P17181

HPA

ENSG00000142166-IFNAR1

ZINC - Substances

INAR1_HUMAN

ZINC target

P17181

Ensembl

ENSG00000142166, ENSP00000270139, ENST00000270139, ENSP00000498654, ENST00000652450

PRO

P17181

Orphanet

29639

ZINC - Predictions - Purchasable

INAR1_HUMAN

PDB

4PO6, 3SE3, 3S98, 3SE4

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P52630 STAT2	4	STAT2 [cytosol] (R-HSA-882029) p-Y-STAT2 [cytosol] (R-HSA-8987235) p-Y690-STAT2 [cytosol] (R-HSA-909683) p-Y690-STAT2 [nucleoplasm] (R-HSA-909673)	0.758	5
UniProt:P42224 STAT1	7	p-STAT1 [cytosol] (R-HSA-8950418) p-STAT1 [nucleoplasm] (R-HSA-8987140) p-Y701-STAT1 [nucleoplasm] (R-HSA-8985905) p-Y701-STAT1 [cytosol] (R-HSA-8951202) p-Y701-STAT1 [nucleoplasm] (R-HSA-6788624) p-Y701-STAT1 [cytosol] (R-HSA-3132766) STAT1 [cytosol] (R-HSA-629622)	0.499	2

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