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IFNG-activated factor (GAF) [nucleoplasm]
Stable Identifier
R-HSA-873824
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
p-STAT1 homodimer
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon gamma signaling (Homo sapiens)
Expression of IFNG-stimulated genes (Homo sapiens)
GAF bound to GAS promoter element [nucleoplasm] (Homo sapiens)
IFNG-activated factor (GAF) [nucleoplasm] (Homo sapiens)
IFNG-activated factor (GAF) [nucleoplasm] (Homo sapiens)
GAF binds the GAS promoter elements in the IFNG-regulated genes (Homo sapiens)
GAF bound to GAS promoter element [nucleoplasm] (Homo sapiens)
IFNG-activated factor (GAF) [nucleoplasm] (Homo sapiens)
IFNG-activated factor (GAF) [nucleoplasm] (Homo sapiens)
Regulation of IFNG signaling (Homo sapiens)
Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP (Homo sapiens)
IFNG-activated factor (GAF) [nucleoplasm] (Homo sapiens)
PIAS1 binds p-STAT1 dimer (Homo sapiens)
IFNG-activated factor (GAF) [nucleoplasm] (Homo sapiens)
p-STAT1 dimer:PIAS:SUMO1 [nucleoplasm] (Homo sapiens)
IFNG-activated factor (GAF) [nucleoplasm] (Homo sapiens)
Translocation of STAT1 dimer to nucleus (Homo sapiens)
IFNG-activated factor (GAF) [nucleoplasm] (Homo sapiens)
Participants
components
2 x
p-S727,Y701-STAT1-1 [nucleoplasm] (Homo sapiens)
Participant Of
input
Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP
GAF binds the GAS promoter elements in the IFNG-regulated genes
PIAS1 binds p-STAT1 dimer
output
Translocation of STAT1 dimer to nucleus
hasComponent
GAF bound to GAS promoter element [nucleoplasm]
p-STAT1 dimer:PIAS:SUMO1 [nucleoplasm]
Inferred To
IFNG-activated factor (GAF) [nucleoplasm] (Bos taurus)
IFNG-activated factor (GAF) [nucleoplasm] (Caenorhabditis elegans)
IFNG-activated factor (GAF) [nucleoplasm] (Canis familiaris)
IFNG-activated factor (GAF) [nucleoplasm] (Danio rerio)
IFNG-activated factor (GAF) [nucleoplasm] (Drosophila melanogaster)
IFNG-activated factor (GAF) [nucleoplasm] (Gallus gallus)
IFNG-activated factor (GAF) [nucleoplasm] (Mus musculus)
IFNG-activated factor (GAF) [nucleoplasm] (Rattus norvegicus)
IFNG-activated factor (GAF) [nucleoplasm] (Sus scrofa)
IFNG-activated factor (GAF) [nucleoplasm] (Taeniopygia guttata)
IFNG-activated factor (GAF) [nucleoplasm] (Xenopus tropicalis)
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