Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
Stable Identifier
R-HSA-873821
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon gamma signaling (Homo sapiens)
Regulation of IFNG signaling (Homo sapiens)
SOCS-1 and SOCS-3 binds to p-JAK2 (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Homo sapiens)
Transphosphorylation of JAK1 (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Homo sapiens)
Participants
components
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane]
(Homo sapiens)
SOCS-1 and SOCS-3 [cytosol]
(Homo sapiens)
Participates
as an output of
SOCS-1 and SOCS-3 binds to p-JAK2 (Homo sapiens)
This entity regulates
Negatively
Transphosphorylation of JAK1
(Homo sapiens)
Inferred To
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
(Bos taurus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
(Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
(Danio rerio)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
(Gallus gallus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
(Mus musculus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
(Rattus norvegicus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
(Sus scrofa)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
