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IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane]
Stable Identifier
R-HSA-873811
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon gamma signaling (Homo sapiens)
Phosphorylation of JAK2 (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
Regulation of IFNG signaling (Homo sapiens)
SOCS-1 and SOCS-3 binds to p-JAK2 (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
Transphosphorylation of JAK1 (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
Participants
components
IFNG homodimer [extracellular region] (Homo sapiens)
IFNGR complex with p-JAK2 [plasma membrane] (Homo sapiens)
Participant Of
input
SOCS-1 and SOCS-3 binds to p-JAK2
Transphosphorylation of JAK1
output
Phosphorylation of JAK2
hasComponent
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
Inferred To
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Bos taurus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Mus musculus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Sus scrofa)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Taeniopygia guttata)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Xenopus tropicalis)
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