Ubiquitinated SMAD4 translocates from the nucleus to the cytosol

Stable Identifier
R-HSA-870477
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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SMAD4 monoubiquitinated by TRIM33 translocates from the nucleus to the cytosol (Dupont et al. 2009, Dupont et al. 2005).

Literature References
PubMed ID Title Journal Year
15820681 Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase

Dupont, S, Zacchigna, L, Cordenonsi, M, Soligo, S, Adorno, M, Rugge, M, Piccolo, S

Cell 2005
19135894 FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination

Dupont, S, Mamidi, A, Cordenonsi, M, Montagner, M, Zacchigna, L, Adorno, M, Martello, G, Stinchfield, MJ, Soligo, S, Morsut, L, Inui, M, Moro, S, Modena, N, Argenton, F, Newfeld, SJ, Piccolo, S

Cell 2009
Participants
Participant Of
Orthologous Events
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