IPAF binds procaspase-1

Stable Identifier
R-HSA-844617
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Salmonella typhimurium
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

IPAF contains an N-terminal CARD domain, a central nucleotide-binding domain, and a C-terminal regulatory leucine-rich repeat domain. IPAF associates with the CARD domain of procaspase-1 through a CARD-CARD interaction.

Literature References
PubMed ID Title Journal Year
11390368 Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

Poyet, JL, Srinivasula, SM, Tnani, M, Razmara, M, Fernandes-Alnemri, T, Alnemri, ES

J Biol Chem 2001
Participants
Participant Of
Authored
Reviewed
Created