IPAF binds procaspase-1

Stable Identifier
R-HSA-844617
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Salmonella typhimurium
Compartment
cytosol
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IPAF binds procaspase-1
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IPAF contains an N-terminal CARD domain, a central nucleotide-binding domain, and a C-terminal regulatory leucine-rich repeat domain. IPAF associates with the CARD domain of procaspase-1 through a CARD-CARD interaction.

Literature References
PubMed ID Title Journal Year
11390368 Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

Srinivasula, SM, Tnani, M, Razmara, M, Poyet, JL, Alnemri, ES, Fernandes-Alnemri, T

J Biol Chem 2001
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Authored
Jupe, S  (2010-04-22)
Reviewed
Kufer, TA  (2011-04-28)
Rittinger, K  (2011-06-06)
Wong, E  (2011-06-06)
Created
Jupe, S  (2010-05-28)
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