IPAF binds procaspase-1

Stable Identifier
R-HSA-844617
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Salmonella typhimurium
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
IPAF binds procaspase-1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

IPAF contains an N-terminal CARD domain, a central nucleotide-binding domain, and a C-terminal regulatory leucine-rich repeat domain. IPAF associates with the CARD domain of procaspase-1 through a CARD-CARD interaction.

Literature References
PubMed ID Title Journal Year
11390368 Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

Poyet, JL, Srinivasula, SM, Tnani, M, Razmara, M, Fernandes-Alnemri, T, Alnemri, ES

J Biol Chem 2001
Participants
Input
Output
Participates
as an event of
Authored
Jupe, S  (2010-04-22)
Reviewed
Kufer, TA  (2011-04-28)
Rittinger, K  (2011-06-06)
Wong, E  (2011-06-06)
Created
Jupe, S  (2010-05-28)
Cite Us!