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SNAPc [nucleoplasm]
Stable Identifier
R-HSA-83730
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA polymerase II transcribes snRNA genes (Homo sapiens)
CBCAP complex binds 7-methylguanosine cap of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
Integrator complex processes the 3' end of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
Pre-snRNA is elongated and capped with 7-methylguanosine (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA Polymerase III Transcription (Homo sapiens)
RNA Polymerase III Abortive And Retractive Initiation (Homo sapiens)
RNA Polymerase III Abortive Initiation At Type 3 Open Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA Polymerase III Promoter Opening at Type 3 Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA Polymerase III Transcription Initiation (Homo sapiens)
RNA Polymerase III Transcription Initiation From Type 3 Promoter (Homo sapiens)
Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Homo sapiens)
SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA Polymerase III Promoter Opening at Type 3 Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
11056176
A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc
Ma, B
,
Hernandez, N
J. Biol. Chem.
2001
Participants
components
SNAPC1 [nucleoplasm]
(Homo sapiens)
SNAPC2 [nucleoplasm]
(Homo sapiens)
SNAPC3 [nucleoplasm]
(Homo sapiens)
SNAPC4 [nucleoplasm]
(Homo sapiens)
SNAPC5 [nucleoplasm]
(Homo sapiens)
Participates
as an input of
Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter (Homo sapiens)
SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
as a component of
SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
Inferred To
SNAPc [nucleoplasm]
(Bos taurus)
SNAPc [nucleoplasm]
(Caenorhabditis elegans)
SNAPc [nucleoplasm]
(Canis familiaris)
SNAPc [nucleoplasm]
(Danio rerio)
SNAPc [nucleoplasm]
(Dictyostelium discoideum)
SNAPc [nucleoplasm]
(Drosophila melanogaster)
SNAPc [nucleoplasm]
(Gallus gallus)
SNAPc [nucleoplasm]
(Mus musculus)
SNAPc [nucleoplasm]
(Rattus norvegicus)
SNAPc [nucleoplasm]
(Saccharomyces cerevisiae)
SNAPc [nucleoplasm]
(Schizosaccharomyces pombe)
SNAPc [nucleoplasm]
(Sus scrofa)
SNAPc [nucleoplasm]
(Xenopus tropicalis)
Cross References
ComplexPortal
CPX-8637
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