C4 deamination of cytidine

Stable Identifier
R-HSA-83677
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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C4 deamination of cytidine
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Hydrolytic deamination of cytidine leads to uridine. Ammonia is presumed to be released during this reaction.
Literature References
PubMed ID Title Journal Year
11718896 Isolation, characterization and developmental regulation of the human apobec-1 complementation factor (ACF) gene.

Davidson, NO, Blanc, V, Henderson, JO

Biochim Biophys Acta 2001
8208612 Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein.

Hadjiagapiou, C, Giannoni, F, Davidson, NO, Funahashi, T, Skarosi, SF

Nucleic Acids Res 1994
Participants
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Output
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as an event of
Catalyst Activity

cytidine deaminase activity of APOBEC1(APOBEC2,3A,3B,3C,3H,4) [nucleoplasm]

Physical Entity
APOBEC1(APOBEC2,3A,3B,3C,3H,4) [nucleoplasm] (Homo sapiens)
Activity
cytidine deaminase activity (GO:0004126)
Orthologous Events
C4 deamination of cytidine (Bos taurus)
C4 deamination of cytidine (Canis familiaris)
C4 deamination of cytidine (Mus musculus)
C4 deamination of cytidine (Rattus norvegicus)
C4 deamination of cytidine (Sus scrofa)
Authored
Gopinathrao, G  (2003-12-05)
Created
Carmichael, GG  (2003-12-05)
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