C4 deamination of cytidine

Stable Identifier
R-HSA-83677
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
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C4 deamination of cytidine
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Hydrolytic deamination of cytidine leads to uridine. Ammonia is presumed to be released during this reaction.

Literature References
PubMed ID Title Journal Year
8208612 Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein.

Hadjiagapiou, C, Giannoni, F, Funahashi, T, Skarosi, SF, Davidson, NO

Nucleic Acids Res 1994
11718896 Isolation, characterization and developmental regulation of the human apobec-1 complementation factor (ACF) gene.

Henderson, JO, Blanc, V, Davidson, NO

Biochim Biophys Acta 2001
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
cytidine deaminase activity of APOBEC1(APOBEC2,3A,3B,3C,3H,4) [nucleoplasm]
Physical Entity
APOBEC1(APOBEC2,3A,3B,3C,3H,4) [nucleoplasm]
Activity
cytidine deaminase activity (0004126)
Orthologous Events
C4 deamination of cytidine (Bos taurus)
C4 deamination of cytidine (Canis familiaris)
C4 deamination of cytidine (Danio rerio)
C4 deamination of cytidine (Mus musculus)
C4 deamination of cytidine (Rattus norvegicus)
C4 deamination of cytidine (Sus scrofa)
C4 deamination of cytidine (Xenopus tropicalis)
Authored
Gopinathrao, G  (2003-12-05)
Created
Carmichael, GG  (2003-12-05)