FasL:Fas binds FADD

Stable Identifier
R-HSA-83650
Type
Reaction
Species
Homo sapiens
Compartment
plasma membrane, cytosol
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FasL:Fas binds FADD
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FADD (FAS-associating death domain-containing) protein binds FASL:FAS receptor trimer through interaction of death domains of FADD and FAS (Boldin et al. 1995).

Literature References
PubMed ID Title Journal Year
7536190 A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

Mett, IL, Wallach, D, Varfolomeev, EE, Camonis, JH, Pancer, Z, Boldin, MP

J Biol Chem 1995
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Orthologous Events
Assembly of the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
Assembly of the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
FasL:Fas binds FADD (Bos taurus)
FasL:Fas binds FADD (Danio rerio)
FasL:Fas binds FADD (Gallus gallus)
FasL:Fas binds FADD (Mus musculus)
FasL:Fas binds FADD (Rattus norvegicus)
FasL:Fas binds FADD (Sus scrofa)
FasL:Fas binds FADD (Xenopus tropicalis)
Authored
Williams, MG  (2007-07-11)
Reviewed
Lemaitre, B  (2008-06-20)
Silverman, N  (2008-06-20)
Salvesen, GS  (2013-05-22)
Pop, C  (2013-05-22)
Created
Tschopp, J  (2004-01-28)
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