Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC

Stable Identifier
R-HSA-77594
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm, nuclear envelope
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The polyadenylated, capped transcript and TAP dock at the nucleoplasmic side of the NPC. The Cap Binding Complex (CBC) and CPSF complexes are released back into the nucleoplasm (Zhou et al. 2000).

Literature References
PubMed ID Title Journal Year
11014198 The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

Reed, R, Luo, MJ, Katahira, J, Hurt, E, Straesser, K, Zhou, Z

Nature 2000
15120988 Nuclear export of mRNA: from the site of transcription to the cytoplasm

Erkmann, JA, Kutay, U

Exp. Cell Res. 2004
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
mRNA export from nucleus (0006406)
This event is regulated
Requirements
Orthologous Events
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Bos taurus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Caenorhabditis elegans)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Canis familiaris)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Drosophila melanogaster)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Mus musculus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Rattus norvegicus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Schizosaccharomyces pombe)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Sus scrofa)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Xenopus tropicalis)
Authored
Gillespie, ME  (2005-01-27)
Created
Wahle, E  (2003-06-05)
Cite Us!