Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC

Stable Identifier
R-HSA-77594
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm, nuclear envelope
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Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC
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The polyadenylated, capped transcript and TAP dock at the nucleoplasmic side of the NPC. The Cap Binding Complex (CBC) and CPSF complexes are released back into the nucleoplasm (Zhou et al. 2000).

Literature References
PubMed ID Title Journal Year
15120988 Nuclear export of mRNA: from the site of transcription to the cytoplasm

Erkmann, JA, Kutay, U

Exp. Cell Res. 2004
11014198 The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

Zhou, Z, Luo, MJ, Straesser, K, Katahira, J, Hurt, E, Reed, R

Nature 2000
Participants
Input
Output
Participant Of
hasEvent
Event Information
Go Biological Process
mRNA export from nucleus (0006406)
This event is regulated
Requirements
Orthologous Events
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Caenorhabditis elegans)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Canis familiaris)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Drosophila melanogaster)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Mus musculus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Rattus norvegicus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Saccharomyces cerevisiae)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Schizosaccharomyces pombe)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Sus scrofa)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Xenopus tropicalis)
Cross References
Target Pathogen
Authored
Gillespie, ME  (2005-01-27)
Created
Wahle, E  (2003-06-05)
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