Cleavage of Intronless Pre-mRNA at 3'-end

Stable Identifier
R-HSA-77592
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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The polypeptide catalyzing the hydrolysis of the phosphodiester bond remains to be identified. Cleavage produces a 3'-OH on the upstream fragment and a 5'-phosphate on the downstream fragment. At some unknown point after cleavage, the downstream fragment, CstF, CF I and CF II are thought to be released, whereas CPSF and poly(A) polymerase remain to carry out polyadenylation.

Participants
Participant Of
Orthologous Events
Authored
Created