(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H

Stable Identifier
R-HSA-77254
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

At the beginning of this reaction, 1 molecule of '(S)-3-Hydroxydodecanoyl-CoA', and 1 molecule of 'NAD+' are present. At the end of this reaction, 1 molecule of 'H+', 1 molecule of '3-Oxododecanoyl-CoA', and 1 molecule of 'NADH' are present.

This reaction takes place in the 'mitochondrial matrix' and is mediated by the '3-hydroxyacyl-CoA dehydrogenase activity' of 'short chain 3-hydroxyacyl-CoA dehydrogenase homodimer'.

Literature References
PubMed ID Title Journal Year
8687463 Human short-chain L-3-hydroxyacyl-CoA dehydrogenase: cloning and characterization of the coding sequence.

Vredendaal, PJ, van den Berg, IE, Malingré, HE, Stroobants, AK, Olde Weghuis, DE, Berger, R

Biochem Biophys Res Commun 1996
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
3-hydroxyacyl-CoA dehydrogenase activity of HADH dimer [mitochondrial matrix]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea