Utilization of Ketone Bodies

Stable Identifier
R-HSA-77108
Type
Pathway
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
Ketone body catabolism
ReviewStatus
5/5
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Utilization of Ketone Bodies
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The levels of acetone in ketone bodies are much lower than those of acetoacetic acid and beta-hydroxybutyric acid. Acetone cannot be converted back to acetyl-CoA, and is excreted in urine, or breathed out through the lungs. Extrahepatic tissues utilize ketone bodies by converting the beta-hydroxybutyrate successively to acetoacetate, acetoacetatyl-CoA, finally to acetyl-CoA (Sass 2011).
Literature References
PubMed ID Title Journal Year
21479626 Inborn errors of ketogenesis and ketone body utilization

Sass, JO

J Inherit Metab Dis 2011
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
ketone body catabolic process (0046952)
Orthologous Events
Utilization of Ketone Bodies (Bos taurus)
Utilization of Ketone Bodies (Caenorhabditis elegans)
Utilization of Ketone Bodies (Canis familiaris)
Utilization of Ketone Bodies (Danio rerio)
Utilization of Ketone Bodies (Dictyostelium discoideum)
Utilization of Ketone Bodies (Drosophila melanogaster)
Utilization of Ketone Bodies (Gallus gallus)
Utilization of Ketone Bodies (Mus musculus)
Utilization of Ketone Bodies (Plasmodium falciparum)
Utilization of Ketone Bodies (Rattus norvegicus)
Utilization of Ketone Bodies (Schizosaccharomyces pombe)
Utilization of Ketone Bodies (Sus scrofa)
Utilization of Ketone Bodies (Xenopus tropicalis)
Authored
Joshi-Tope, G  (2003-10-19)
Created
Gopinathrao, G  (2003-10-16)
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