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RNMT [nucleoplasm]
Stable Identifier
R-HSA-77060
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RNA (guanine-7-) methyltransferase
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Transcription of the HIV genome (Homo sapiens)
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection (Homo sapiens)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Pol II CTD phosphorylation and interaction with CE (Homo sapiens)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
mRNA Capping (Homo sapiens)
Capping complex formation (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Capping complex (initial) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Dissociation of transcript with 5'-GMP from GT (Homo sapiens)
Capping complex (GpppN..) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Formation of the CE:GMP intermediate complex (Homo sapiens)
Capping complex (intermediate) [nucleoplasm] (Homo sapiens)
Covalent CE:GMP intermediate complex [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Capping complex (hydrolyzed) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Homo sapiens)
Capping complex (hydrolyzed) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Capping complex (initial) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Methylation of GMP-cap by RNA Methyltransferase (Homo sapiens)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
mRNA capping factors [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Homo sapiens)
Capping complex (intermediate) [nucleoplasm] (Homo sapiens)
Covalent CE:GMP intermediate complex [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
Capping complex (GpppN..) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
RNMT [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43148 RNMT
Gene Names
RNMT, KIAA0398
Chain
chain:1-476
Reference Genes
BioGPS Gene:8731 RNMT
COSMIC (genes):RNMT RNMT
CTD Gene:8731 RNMT
dbSNP Gene:8731 RNMT
ENSEMBL:ENSG00000101654 RNMT
HGNC:10075 RNMT
KEGG:hsa:8731 RNMT
Monarch:8731 RNMT
NCBI Gene:8731 RNMT
OMIM:603514 RNMT
UCSC:O43148 RNMT
Reference Transcript
RefSeq:XM_005258162.1 RNMT
RefSeq:NM_001308263.1 RNMT
RefSeq:XM_017026061.1 RNMT
RefSeq:NM_003799.2 RNMT
Other Identifiers
11728296_a_at
11728297_a_at
11744569_a_at
11751733_a_at
16851206
202683_PM_s_at
202683_s_at
202684_PM_s_at
202684_s_at
3780290
3780291
3780292
3780294
3780295
3780296
3780297
3780298
3780299
3780300
3780301
3780302
3780303
3780304
3780305
3780306
3780312
3780313
3780314
3780315
3780316
3780317
3780318
38073_at
8020323
8731
A_14_P101823
A_14_P129075
A_23_P55515
A_24_P48408
GE53159
GO:0001650
GO:0003723
GO:0003824
GO:0004482
GO:0005515
GO:0005634
GO:0005654
GO:0006370
GO:0008168
GO:0016071
GO:0016740
GO:0031533
GO:0032259
GO:0043226
GO:0043235
GO:0106005
GO:0140098
GO:0160130
GO:1990830
HMNXSV003044055
ILMN_1769637
PH_hs_0000865
TC18000074.hg
g4506566_3p_a_at
g5478274_3p_a_at
Participates
as a component of
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
mRNA capping factors [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
as an input of
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Homo sapiens)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Homo sapiens)
Inferred To
RNMT [nucleoplasm]
(Bos taurus)
RNMT [nucleoplasm]
(Caenorhabditis elegans)
RNMT [nucleoplasm]
(Canis familiaris)
RNMT [nucleoplasm]
(Danio rerio)
RNMT [nucleoplasm]
(Dictyostelium discoideum)
RNMT [nucleoplasm]
(Drosophila melanogaster)
RNMT [nucleoplasm]
(Gallus gallus)
RNMT [nucleoplasm]
(Mus musculus)
RNMT [nucleoplasm]
(Plasmodium falciparum)
RNMT [nucleoplasm]
(Rattus norvegicus)
RNMT [nucleoplasm]
(Saccharomyces cerevisiae)
RNMT [nucleoplasm]
(Schizosaccharomyces pombe)
RNMT [nucleoplasm]
(Sus scrofa)
RNMT [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_003790.1
,
NP_001295192.1
,
XP_016881550.1
,
XP_005258219.1
OpenTargets
ENSG00000101654
ENSEMBL
ENSP00000446426
,
ENST00000592764
,
ENSP00000466252
,
ENSP00000466111
,
ENST00000589866
,
ENST00000262173
,
ENSP00000372804
,
ENSP00000262173
,
ENST00000543302
,
ENST00000383314
HPA
ENSG00000101654-RNMT
PRO
O43148
Pharos - Targets
O43148
GlyGen
O43148
PDB
3EPP
,
5E9W
,
3BGV
,
5E9J
,
5E8J
HMDB Protein
HMDBP09016
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BTL3 RAMAC
0.75
9
UniProt:O60684 KPNA6
2
KPNA6 [nucleoplasm]
(R-HSA-9734665)
KPNA6 [cytosol]
(R-HSA-9734672)
0.742
6
UniProt:P52292 KPNA2
2
KPNA2 [cytosol]
(R-HSA-205976)
KPNA2 [nucleoplasm]
(R-HSA-206045)
0.666
4
UniProt:P52294 KPNA1
2
KPNA1 [cytosol]
(R-HSA-180612)
KPNA1 [nucleoplasm]
(R-HSA-188865)
0.643
4
UniProt:Q9HB20 PLEKHA3
1
PLEKHA3 [Golgi membrane]
(R-HSA-8870513)
0.556
3
UniProt:Q96IK5 GMCL1
0.556
3
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