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PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
Stable Identifier
R-HSA-75907
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA-PK:DNA complex, DNA-PK holoenzyme
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Nonhomologous End-Joining (NHEJ) (Homo sapiens)
Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Homo sapiens)
PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm] (Homo sapiens)
DNA-PKcs autophosphorylates (Homo sapiens)
PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm] (Homo sapiens)
Participants
components
DNA double-strand break ends [nucleoplasm]
x 2
PRKDC:XRCC5:XRCC6 heterotrimer [nucleoplasm]
(Homo sapiens)
Participates
as an input of
DNA-PKcs autophosphorylates (Homo sapiens)
as an output of
Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Homo sapiens)
Inferred To
PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
(Bos taurus)
PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
(Canis familiaris)
PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
(Dictyostelium discoideum)
PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
(Gallus gallus)
PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
(Mus musculus)
PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
(Rattus norvegicus)
PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
(Sus scrofa)
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