Ubiquitination of Cyclin D1

Stable Identifier
R-HSA-75824
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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Ubiquitination of Cyclin D1
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Cyclin D is targeted for degradation by multi-ubiquitination.

Literature References
PubMed ID Title Journal Year
9136925 Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

Diehl, JA, Zindy, F, Sherr, CJ

Genes Dev 1997
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
ubiquitin-protein transferase activity of Ubiquitin ligase [cytosol]
Physical Entity
Ubiquitin ligase [cytosol]
Activity
ubiquitin-protein transferase activity (0004842)
Authored
Matthews, L  (2006-04-14)
Created
Matthews, L  (2003-09-01)