Ubiquitination of Cyclin D1

Stable Identifier
R-HSA-75824
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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Cyclin D is targeted for degradation by multi-ubiquitination.
Literature References
PubMed ID Title Journal Year
9136925 Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

Sherr, CJ, Zindy, F, Diehl, JA

Genes Dev 1997
Participants
Participates
Catalyst Activity

ubiquitin-protein transferase activity of Ubiquitin ligase [cytosol]

Authored
Created
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