Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction

Stable Identifier
R-HSA-75174
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction
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NBN (NBS1) binds MRE11A:RAD50 complex to form the evolutionarily conserved MRN complex (Trujillo et al. 1998).

Literature References
PubMed ID Title Journal Year
9705271 Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95.

Trujillo, KM, Yuan, SS, Lee, EY, Sung, P

J Biol Chem 1998
Participants
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Orthologous Events
Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Bos taurus)
Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Canis familiaris)
Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Danio rerio)
Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Drosophila melanogaster)
Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Mus musculus)
Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Rattus norvegicus)
Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Schizosaccharomyces pombe)
Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Sus scrofa)
Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Xenopus tropicalis)
Authored
Lees-Miller, S  (2003-07-14)
Thompson, L  (2003-07-14)
Reviewed
Borowiec, JA  (2015-06-12)
Created
Thompson, L  (2003-07-14)