Reactome | C6 deamination of adenosine

Stable Identifier

R-HSA-75102

Type

Pathway

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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Hydrolytic deamination of adenosine leads to inosine. Ammonia is presumed to be released during this reaction.

Literature References

PubMed ID	Title	Journal	Year
9111310	Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases. Nishikura, K, Carter, KC, Lai, F, Chen, CX	Mol Cell Biol	1997
7565688	Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase. Samuel, CE, Patterson, JB	Mol Cell Biol	1995