Reactome | ATAC spliceosome mediated Lariat formation,5' splice site cleavage

ATAC spliceosome mediated Lariat formation,5' splice site cleavage

Stable Identifier

R-HSA-75082

Type

Reaction [transition]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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ATAC spliceosome mediated Lariat formation,5' splice site cleavage

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At the beginning of this reaction, 1 molecule of 'ATAC C Complex' is present. At the end of this reaction, 1 molecule of 'ATAC C Complex with lariat containing 5'-end cleaved mRNA' is present.

This reaction takes place in the 'nucleus' (Valadkhan and Manley 2001, Valadkhan et al. 2007).

Literature References

PubMed ID	Title	Journal	Year
17940139	Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing Manley, JL, Mohammadi, A, Wachtel, C, Valadkhan, S	RNA	2007
11607023	Splicing-related catalysis by protein-free snRNAs Valadkhan, S, Manley, JL	Nature	2001