Phosphorylation of Cdc25C at Ser 216 by Chk1

Stable Identifier
R-HSA-75010
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Phosphorylation of Cdc25C at Ser 216 results in both the inhibition of Cdc25C phosphatase activity and the creation of a 14-3-3 docking site (Peng et al. 1997).

Literature References
PubMed ID Title Journal Year
9278512 Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216.

Peng, CY, Graves, PR, Thoma, RS, Wu, Z, Shaw, AS, Piwnica-Worms, H

Science 1997
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of p-S317,S345-CHEK1 [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Created