Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
GUCY2D [photoreceptor disc membrane]
Stable Identifier
R-HSA-74914
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
photoreceptor disc membrane
Synonyms
Retinal guanylyl cyclase 1 precursor , Guanylate cyclase 2D, retinal, RETGC-1, Rod outer segment membrane guanylate cyclase, ROS-GC
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
The phototransduction cascade (Homo sapiens)
Inactivation, recovery and regulation of the phototransduction cascade (Homo sapiens)
GUCYs converts GTP to cGMP (Homo sapiens)
GUCYs [photoreceptor disc membrane] (Homo sapiens)
GUCY2D [photoreceptor disc membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02846 GUCY2D
Gene Names
GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Chain
signal peptide:1-51, chain:52-1103
Reference Genes
BioGPS Gene:3000 GUCY2D
COSMIC (genes):GUCY2D GUCY2D
CTD Gene:3000 GUCY2D
dbSNP Gene:3000 GUCY2D
ENSEMBL:ENSG00000132518 GUCY2D
HGNC:4689 GUCY2D
KEGG Gene (Homo sapiens):3000 GUCY2D
Monarch:3000 GUCY2D
NCBI Gene:3000 GUCY2D
OMIM:600179 GUCY2D
UCSC:Q02846 GUCY2D
Reference Transcript
RefSeq:NM_000180.3 GUCY2D
RefSeq:XM_011523816.1 GUCY2D
Other Identifiers
0003130398
11734611_at
16830863
207884_at
3000
31977_at
3709387
3709388
3709389
3709390
3709391
3709392
3709393
3709394
3709395
3709396
3709398
3709399
3709400
3709401
3709403
3709404
3709406
3709407
3709408
3709409
3709416
8004763
A_23_P130259
GO:0000166
GO:0001653
GO:0001750
GO:0003674
GO:0004383
GO:0004672
GO:0005515
GO:0005524
GO:0005525
GO:0005575
GO:0005622
GO:0005634
GO:0005635
GO:0005640
GO:0005737
GO:0005783
GO:0005789
GO:0005886
GO:0005887
GO:0005929
GO:0006182
GO:0006464
GO:0006468
GO:0007165
GO:0007168
GO:0007601
GO:0008150
GO:0009058
GO:0009190
GO:0016020
GO:0016021
GO:0016301
GO:0016829
GO:0016849
GO:0022400
GO:0034641
GO:0035556
GO:0038023
GO:0042622
GO:0042803
GO:0042995
GO:0043167
GO:0043226
GO:0044281
GO:0050877
GO:0050896
GO:0097381
HMNXSV003039063
ILMN_1725410
ILMN_1795842
M92432_at
PH_hs_0023701
TC17000123.hg
g4504216_3p_at
Participates
as a member of
GUCYs [photoreceptor disc membrane] (Homo sapiens)
Inferred To
acgA [photoreceptor disc membrane]
(Dictyostelium discoideum)
GUCY2D [photoreceptor disc membrane]
(Bos taurus)
GUCY2D [photoreceptor disc membrane]
(Canis familiaris)
GUCY2D [photoreceptor disc membrane]
(Sus scrofa)
gca [photoreceptor disc membrane]
(Dictyostelium discoideum)
gc2 [photoreceptor disc membrane]
(Danio rerio)
CG9783 [photoreceptor disc membrane]
(Drosophila melanogaster)
Gucy2e [photoreceptor disc membrane]
(Mus musculus)
Gucy2e [photoreceptor disc membrane]
(Rattus norvegicus)
Homologues of GUCY2D [photoreceptor disc membrane]
(Dictyostelium discoideum)
Cross References
RefSeq
XP_011522118.1
,
NP_000171.1
Guide to Pharmacology - Targets
2031
OpenTargets
ENSG00000132518
GeneCards
Q02846
HPA
ENSG00000132518-GUCY2D
Ensembl
ENSG00000132518
,
ENSP00000254854
,
ENST00000254854
PRO
Q02846
Pharos - Targets
Q02846
GlyGen
Q02846
Orphanet
16178
HMDB Protein
HMDBP01067
© 2022
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text