Insulin receptor

Stable Identifier
R-HSA-74675
Type
Complex
Species
Homo sapiens
Compartment
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Summation

The human insulin receptor is expressed as two isoforms that are generated by alternate splicing of its mRNA; the B isoform has 12 additional amino acids (718-729) encoded by exon 11 of the gene.

Literature References
PubMed ID Title Journal Year
2859121 The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling.

Ebina, Y, Ellis, L, Jarnagin, K, Edery, M, Graf, L, Clauser, E, Ou, JH, Masiarz, F, Kan, YW, Goldfine, ID

Cell 1985
2983222 Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes.

Ullrich, A, Bell, JR, Chen, EY, Herrera, R, Petruzzelli, LM, Dull, TJ, Gray, A, Coussens, L, Liao, YC, Tsubokawa, M

Nature 1985
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