SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen

Stable Identifier
R-HSA-742373
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi membrane
ReviewStatus
5/5
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SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen
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The human gene SLC35B4 encodes the bifunctional UDP-xylose and UDP-N-acetylglucosamine transporter YEA4. YEA4 resides on the Golgi membrane and mediates the influx of UDP-xylose into the lumen (Ashikov A et al, 2005).
Literature References
PubMed ID Title Journal Year
15911612 The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine

Ashikov, A, Routier, F, Fuhlrott, J, Helmus, Y, Wild, M, Gerardy-Schahn, R, Bakker, H

J Biol Chem 2005
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Catalyst Activity

UDP-xylose transmembrane transporter activity of SLC35B4 [Golgi membrane]

Physical Entity
SLC35B4 [Golgi membrane] (Homo sapiens)
Activity
UDP-xylose transmembrane transporter activity (GO:0005464)
Orthologous Events
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Bos taurus)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Caenorhabditis elegans)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Canis familiaris)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Danio rerio)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Dictyostelium discoideum)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Drosophila melanogaster)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Gallus gallus)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Mus musculus)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Rattus norvegicus)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Saccharomyces cerevisiae)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Schizosaccharomyces pombe)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Sus scrofa)
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Xenopus tropicalis)
Authored
Jassal, B  (2010-05-17)
Reviewed
He, L  (2010-05-10)
Created
Jassal, B  (2010-05-17)
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