SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen

Stable Identifier
R-HSA-742354
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The human gene SLC35B4 encodes the bifunctional UDP-xylose and UDP-N-acetylglucosamine transporter YEA4. YEA4 resides on the Golgi membrane and mediates the influx of UDP-N-acetylglucosamine into the lumen (Ashikov A et al, 2005).

Literature References
PubMed ID Title Journal Year
15911612 The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine

Wild, M, Routier, F, Helmus, Y, Fuhlrott, J, Gerardy-Schahn, R, Bakker, H, Ashikov, A

J Biol Chem 2005
Participants
Input
Output
Participates
as an event of
Catalyst Activity

UDP-N-acetylglucosamine transmembrane transporter activity of SLC35B4 [Golgi membrane]

Physical Entity
SLC35B4 [Golgi membrane] (Homo sapiens)
Activity
UDP-N-acetylglucosamine transmembrane transporter activity (GO:0005462)
Orthologous Events
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Bos taurus)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Caenorhabditis elegans)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Canis familiaris)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Danio rerio)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Dictyostelium discoideum)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Drosophila melanogaster)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Gallus gallus)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Mus musculus)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Rattus norvegicus)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Saccharomyces cerevisiae)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Schizosaccharomyces pombe)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Sus scrofa)
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Xenopus tropicalis)
Authored
Jassal, B  (2010-05-17)
Reviewed
He, L  (2010-05-10)
Created
Jassal, B  (2010-05-17)
Cite Us!