Reactome | D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

Stable Identifier

R-HSA-73920

Type

Reaction [transition]

Species

Homo sapiens

Compartment

mitochondrial matrix

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

D-beta-hydroxybutyrate dehydrogenase tetramer (BDH1) in the mitochondrial matrix catalyzes the reversible reaction of D-beta hydroxybutyrate and NAD+ to form acetoacetate and NADH + H+ (Marks et al. 1992).

Literature References

PubMed ID	Title	Journal	Year
1639787	Molecular cloning and characterization of (R)-3-hydroxybutyrate dehydrogenase from human heart Marks, AR, McIntyre, JO, Duncan, TM, Erdjument-Bromage, H, Tempst, P, Fleischer, S	J Biol Chem	1992