Reactome | D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

Stable Identifier

R-HSA-73920

Type

Reaction [transition]

Species

Homo sapiens

Compartment

mitochondrial matrix

ReviewStatus

5/5

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D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

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D-beta-hydroxybutyrate dehydrogenase tetramer (BDH1) in the mitochondrial matrix catalyzes the reversible reaction of D-beta hydroxybutyrate and NAD+ to form acetoacetate and NADH + H+ (Marks et al. 1992).

Literature References

PubMed ID	Title	Journal	Year
1639787	Molecular cloning and characterization of (R)-3-hydroxybutyrate dehydrogenase from human heart Duncan, TM, McIntyre, JO, Fleischer, S, Tempst, P, Erdjument-Bromage, H, Marks, AR	J Biol Chem	1992