2 acetyl-CoA <=> acetoacetyl-CoA + CoA

Stable Identifier
R-HSA-73916
Type
Reaction
Species
Homo sapiens
Compartment
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Acetyl-CoA acetyltransferase tetramer (ACAT1) in the mitochondrial matrix catalyzes the reversible reaction of two molecules of acetyl-CoA to form acetoacetyl-CoA and CoA (Middleton et al. 1986).

Literature References
PubMed ID Title Journal Year
3709573 3-Ketothiolase deficiency

Romanos, A, Middleton, B, Cannon, RA, Conde, C, Nyhan, WL, Lipson, M, Gomez Vazquez, J, Bartlett, K, Sweetman, L

Eur J Pediatr 1986
Participants
Participates
Catalyst Activity

acetyl-CoA C-acetyltransferase activity of ACAT1 tetramer [mitochondrial matrix]

Orthologous Events
Cross References
Rhea
Created
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