RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

Stable Identifier
R-HSA-73779
Type
Pathway
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
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Formation of the pre-initiation complex proceeds in five steps, recognition and binding of core promoter elements by TFIID, binding of TFIIA and TFIIB to the pol II promoter:TFIID complex, recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex, binding of TFIIE to the growing preinitiation complex, and formation of the closed pre-initiation complex (Orphanides et al. 1997).

Literature References
PubMed ID Title Journal Year
8946909 The general transcription factors of RNA polymerase II.

Orphanides, G, Reinberg, D, Lagrange, T

Genes Dev 1997
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
transcription initiation from RNA polymerase II promoter (0006367)
Orthologous Events
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RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Danio rerio)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Dictyostelium discoideum)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Drosophila melanogaster)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Gallus gallus)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Mus musculus)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Rattus norvegicus)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Saccharomyces cerevisiae)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Schizosaccharomyces pombe)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Sus scrofa)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Xenopus tropicalis)
Authored
Reinberg, D  (2003-09-11)
Created
Reinberg, D  (2003-09-11)
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