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RRM1 [cytosol]
Stable Identifier
R-HSA-73638
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
ribonucleotide reductase M1 polypeptide, Ribonucleoside-diphosphate reductase M1 chain (EC 1.17.4.1) (Ribonucleotide reductase large chain), Ribonucleoside-diphosphate reductase M1 chain , Ribonucleotide reductase large chain
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Interconversion of nucleotide di- and triphosphates (Homo sapiens)
RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Homo sapiens)
RNR (M1M2) [cytosol] (Homo sapiens)
RRM1 dimer [cytosol] (Homo sapiens)
RRM1 [cytosol] (Homo sapiens)
RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Homo sapiens)
RNR (M1M2) [cytosol] (Homo sapiens)
RRM1 dimer [cytosol] (Homo sapiens)
RRM1 [cytosol] (Homo sapiens)
RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Homo sapiens)
RNR (M1M2B) [cytosol] (Homo sapiens)
RRM1 dimer [cytosol] (Homo sapiens)
RRM1 [cytosol] (Homo sapiens)
RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Homo sapiens)
RNR (M1M2B) [cytosol] (Homo sapiens)
RRM1 dimer [cytosol] (Homo sapiens)
RRM1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P23921 RRM1
Gene Names
RRM1, RR1
Chain
chain:1-792
Reference Genes
BioGPS Gene:6240 RRM1
COSMIC (genes):RRM1 RRM1
CTD Gene:6240 RRM1
dbSNP Gene:6240 RRM1
ENSEMBL:ENSG00000167325 RRM1
HGNC:10451 RRM1
KEGG Gene (Homo sapiens):6240 RRM1
Monarch:6240 RRM1
NCBI Gene:6240 RRM1
OMIM:180410 RRM1
UCSC:P23921 RRM1
Reference Transcript
RefSeq:NM_001033.4 RRM1
RefSeq:NM_001318065.1 RRM1
RefSeq:NM_001318064.1 RRM1
Other Identifiers
0004730722
11743602_a_at
11743603_a_at
11743604_s_at
11750667_a_at
16721126
201476_s_at
201477_s_at
3318010
3318017
3318019
3318020
3318022
3318023
3318024
3318025
3318027
3318028
3318030
3318031
3318032
3318033
3318034
3318035
3318036
3318038
3318039
3318040
3318041
3318042
3318043
3318044
3318045
34314_at
6240
7937915
A_23_P87351
GO:0000003
GO:0000166
GO:0000278
GO:0003674
GO:0003824
GO:0004748
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005635
GO:0005737
GO:0005829
GO:0005971
GO:0006206
GO:0006260
GO:0007049
GO:0008150
GO:0008152
GO:0008283
GO:0008584
GO:0009058
GO:0009263
GO:0010212
GO:0015949
GO:0016491
GO:0017076
GO:0021846
GO:0022607
GO:0032991
GO:0034641
GO:0042802
GO:0042995
GO:0043025
GO:0043167
GO:0043226
GO:0044281
GO:0048856
GO:0051290
GO:0055114
GO:0060041
GO:0061731
GO:0065003
GO:0097718
Hs.2934.0.A1_3p_a_at
ILMN_1771593
PH_hs_0018698
TC11000090.hg
X59543_at
g4506748_3p_a_at
Participant Of
hasComponent
RRM1 dimer [cytosol]
Inferred To
Rrm1 [cytosol] (Mus musculus)
Rrm1 [cytosol] (Rattus norvegicus)
rnr-1 [cytosol] (Caenorhabditis elegans)
cdc22 [cytosol] (Schizosaccharomyces pombe)
RnrL [cytosol] (Drosophila melanogaster)
rnrA [cytosol] (Dictyostelium discoideum)
RRM1 [cytosol] (Canis familiaris)
RRM1 [cytosol] (Gallus gallus)
RRM1 [cytosol] (Plasmodium falciparum)
RRM1 [cytosol] (Sus scrofa)
rrm1 [cytosol] (Danio rerio)
rrm1 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
NP_001304993.1
,
NP_001024.1
,
NP_001304994.1
OpenTargets
ENSG00000167325
HPA
ENSG00000167325-RRM1
ZINC - Substances
RIR1_HUMAN
GeneCards
P23921
Ensembl
ENSP00000300738
,
ENST00000300738
,
ENSG00000167325
ZINC target
P23921
PRO
P23921
ZINC - Predictions - Purchasable
RIR1_HUMAN
HMDB Protein
HMDBP00108
PDB
6AUI
,
3HND
,
3HNF
,
4X3V
,
5TUS
,
5D1Y
,
3HNC
,
3HNE
,
2WGH
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P31350 RRM2
1
RRM2 [cytosol]
(R-HSA-73639)
0.806
6
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