Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Pyrimidine salvage
Stable Identifier
R-HSA-73614
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide salvage (Homo sapiens)
Pyrimidine salvage (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
Click the image above or
here
to open this pathway in the Pathway Browser
In pyrimidine salvage reactions, nucleosides and free bases generated by DNA and RNA breakdown are converted back to nucleotide monophosphates, allowing them to re-enter the pathways of pyrimidine biosynthesis and interconversion.
Participants
Events
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2]
(Homo sapiens)
uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]
(Homo sapiens)
thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP]
(Homo sapiens)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1]
(Homo sapiens)
UCKL1 phosphorylates urindine, cytidine
(Homo sapiens)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]
(Homo sapiens)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]
(Homo sapiens)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK)
(Homo sapiens)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)
(Homo sapiens)
HDHD1:Mg2+ dephosphorylates PURIDP
(Homo sapiens)
Participates
as an event of
Nucleotide salvage (Homo sapiens)
Event Information
Go Biological Process
pyrimidine nucleoside salvage (0043097)
Orthologous Events
Pyrimidine salvage (Bos taurus)
Pyrimidine salvage (Caenorhabditis elegans)
Pyrimidine salvage (Canis familiaris)
Pyrimidine salvage (Danio rerio)
Pyrimidine salvage (Dictyostelium discoideum)
Pyrimidine salvage (Drosophila melanogaster)
Pyrimidine salvage (Gallus gallus)
Pyrimidine salvage (Mus musculus)
Pyrimidine salvage (Plasmodium falciparum)
Pyrimidine salvage (Rattus norvegicus)
Pyrimidine salvage (Saccharomyces cerevisiae)
Pyrimidine salvage (Schizosaccharomyces pombe)
Pyrimidine salvage (Sus scrofa)
Pyrimidine salvage (Xenopus tropicalis)
Authored
Jassal, B (2003-06-17)
Created
Jassal, B (2003-06-17)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text