Formation of the cap-binding eIF4F complex

Stable Identifier
R-HSA-72631
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
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Formation of the cap-binding eIF4F complex
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eIF4A interacts with eIF4G, and eIF4E interacts with the amino-terminal domain of eIF4G to form the cap-binding complex eIF4F.

Literature References
PubMed ID Title Journal Year
8449919 The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4A.

Yoder-Hill, J, Merrick, WC, Pause, A, Sonenberg, N

J Biol Chem 1993
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Orthologous Events
Formation of the cap-binding eIF4F complex (Caenorhabditis elegans)
Formation of the cap-binding eIF4F complex (Canis familiaris)
Formation of the cap-binding eIF4F complex (Danio rerio)
Formation of the cap-binding eIF4F complex (Dictyostelium discoideum)
Formation of the cap-binding eIF4F complex (Drosophila melanogaster)
Formation of the cap-binding eIF4F complex (Mus musculus)
Formation of the cap-binding eIF4F complex (Plasmodium falciparum)
Formation of the cap-binding eIF4F complex (Rattus norvegicus)
Formation of the cap-binding eIF4F complex (Saccharomyces cerevisiae)
Formation of the cap-binding eIF4F complex (Schizosaccharomyces pombe)
Formation of the cap-binding eIF4F complex (Sus scrofa)
Formation of the cap-binding eIF4F complex (Xenopus tropicalis)
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