Formation of pre-mRNPs

Stable Identifier
R-HSA-72103
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Formation of pre-mRNPs
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

After the nascent pre-mRNA undergoes the initial capping and methylation reactions, it gets associated with numerous factors, including the various heterogeneous nuclear ribonucleoproteins (hnRNPS), the nuclear Cap-Binding Complex, and many splicing factors that make the pre-mRNA a substrate for splicing, 3'-end processing, and in some cases editing.

Literature References
PubMed ID Title Journal Year
8352591 hnRNP proteins and the biogenesis of mRNA

Piñol-Roma, S, Matunis, MJ, Burd, CG, Dreyfuss, G

Annu. Rev. Biochem. 1993
Participants
Input
Output
Participates
as an event of
Orthologous Events
Formation of pre-mRNPs (Canis familiaris)
Formation of pre-mRNPs (Mus musculus)
Created
Krainer, AR  (2003-06-05)
Cite Us!