Formation of pre-mRNPs

Stable Identifier
R-HSA-72103
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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Formation of pre-mRNPs
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After the nascent pre-mRNA undergoes the initial capping and methylation reactions, it gets associated with numerous factors, including the various heterogeneous nuclear ribonucleoproteins (hnRNPS), the nuclear Cap-Binding Complex, and many splicing factors that make the pre-mRNA a substrate for splicing, 3'-end processing, and in some cases editing.

Literature References
PubMed ID Title Journal Year
8352591 hnRNP proteins and the biogenesis of mRNA

Piñol-Roma, S, Matunis, MJ, Burd, CG, Dreyfuss, G

Annu. Rev. Biochem. 1993
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Orthologous Events
Formation of pre-mRNPs (Bos taurus)
Formation of pre-mRNPs (Caenorhabditis elegans)
Formation of pre-mRNPs (Canis familiaris)
Formation of pre-mRNPs (Danio rerio)
Formation of pre-mRNPs (Dictyostelium discoideum)
Formation of pre-mRNPs (Drosophila melanogaster)
Formation of pre-mRNPs (Gallus gallus)
Formation of pre-mRNPs (Mus musculus)
Formation of pre-mRNPs (Plasmodium falciparum)
Formation of pre-mRNPs (Rattus norvegicus)
Formation of pre-mRNPs (Saccharomyces cerevisiae)
Formation of pre-mRNPs (Schizosaccharomyces pombe)
Formation of pre-mRNPs (Sus scrofa)
Formation of pre-mRNPs (Xenopus tropicalis)
Created
Krainer, AR  (2003-06-05)
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