Reactome | METTL14 [nucleoplasm]

METTL14 [nucleoplasm]

Stable Identifier

R-HSA-72092

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

MT-B, MET14_HUMAN, N6-adenosine-methyltransferase subunit METTL14 ecNumber evidence="5"2.1.1.62/ecNumber, KIAA1627

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9HCE5 METTL14

Gene Names

METTL14, KIAA1627

Chain

chain:1-456

Reference Genes

BioGPS Gene:57721 METTL14

COSMIC (genes):METTL14 METTL14

CTD Gene:57721 METTL14

dbSNP Gene:57721 METTL14

ENSEMBL:ENSG00000145388 METTL14

HGNC:29330 METTL14

Monarch:57721 METTL14

NCBI Gene:57721 METTL14

OMIM:616504 METTL14

UCSC:Q9HCE5 METTL14

Reference Transcript

RefSeq:NM_020961.3 METTL14

Other Identifiers

11742808_at

16970096

227601_PM_at

227601_at

235552_PM_at

235552_at

236060_PM_at

236060_at

241689_PM_at

241689_at

2741084

2741085

2741087

2741088

2741089

2741090

2741091

2741092

2741093

2741094

2741097

2741100

2741101

2741102

2741103

2741104

2741105

2741106

2741108

2741110

2741112

2741114

57721

68373_r_at

77204_at

77303_at

8097066

83884_at

90545_at

A_14_P109706

A_23_P110243

A_32_P54186

GE79616

GE88401

GO:0000398

GO:0001510

GO:0001734

GO:0003723

GO:0003729

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0006397

GO:0007283

GO:0008757

GO:0016071

GO:0016556

GO:0016740

GO:0019827

GO:0021861

GO:0022414

GO:0030154

GO:0036396

GO:0042063

GO:0043226

GO:0045664

GO:0045727

GO:0048255

GO:0061157

GO:0140098

GO:1901533

HMNXSV003029630

HMNXSV003040968

Hs.127685.0.S1_3p_at

Hs.157149.0.A1_3p_at

Hs.158958.0.A1_3p_at

Hs.158958.0.A1_3p_x_at

Hs.171397.0.A1_3p_at

ILMN_2124523

PH_hs_0022742

TC04000608.hg

Participates

as a component of

mRNA (N6-adenosine)-methyltransferase [nucleoplasm] (Homo sapiens)

Inferred To

Mettl14 [nucleoplasm] (Drosophila melanogaster)

Mettl14 [nucleoplasm] (Mus musculus)

METTL14 [nucleoplasm] (Bos taurus)

METTL14 [nucleoplasm] (Canis familiaris)

METTL14 [nucleoplasm] (Gallus gallus)

METTL14 [nucleoplasm] (Plasmodium falciparum)

METTL14 [nucleoplasm] (Rattus norvegicus)

METTL14 [nucleoplasm] (Sus scrofa)

mettl14 [nucleoplasm] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000145388

ENSEMBL

ENSP00000373474, ENST00000388822

HPA

ENSG00000145388-METTL14

PRO

Q9HCE5

Pharos - Targets

Q9HCE5

PDB

6TTP, 7OEM, 7O2X, 6TTV, 6Y4G, 7O29, 5K7U, 5TEY, 7O0P, 7RX7, 7NHJ, 7O0R, 8BN8, 7O08, 7O0L, 7OED, 7OEI, 7OEK, 5IL2, 7OEH, 7OQL, 7OEF, 5L6D, 7NHV, 7NI9, 7O2H, 7O2I, 7O2E, 6TTT, 6TU1, 7NHH, 6TTW, 7O09, 7O28, 7O27, 6TTX, 5K7M, 7NHI, 5IL0, 7OEG, 7NHG, 5K7W, 5IL1, 7OQO, 7O0M, 7OQP, 7OEJ, 7OEL, 7OEE, 7RX8, 7O0Q, 7RX6, 7ACD, 7NI8, 7NI7, 7NID, 7O2F, 7NIA, 5L6E

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