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METTL3 [nucleoplasm]
Stable Identifier
R-HSA-72091
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
MT-A70, N6-adenosine-methyltransferase 70 kDa subunit , Methyltransferase-like protein 3
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Internal Methylation of mRNA (Homo sapiens)
mRNA (N6-adenosine)-methyltransferase [nucleoplasm] (Homo sapiens)
METTL3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86U44 METTL3
Gene Names
METTL3, MTA70
Chain
initiator methionine:, chain:2-580
Reference Genes
BioGPS Gene:56339 METTL3
COSMIC (genes):METTL3 METTL3
CTD Gene:56339 METTL3
dbSNP Gene:56339 METTL3
ENSEMBL:ENSG00000165819 METTL3
ENSEMBL_homo_sapiens_GENE:ENSG00000165819.12 METTL3
HGNC:17563 METTL3
KEGG Gene (Homo sapiens):56339 METTL3
Monarch:56339 METTL3
NCBI Gene:56339 METTL3
OMIM:612472 METTL3
UCSC:Q86U44 METTL3
Reference Transcript
RefSeq:NM_019852.4 METTL3
Other Identifiers
11717975_a_at
11717976_x_at
11746193_a_at
11746194_x_at
11748568_a_at
16790381
209265_PM_s_at
209265_s_at
32246_g_at
3556419
3556420
3556421
3556424
3556426
3556428
3556429
3556434
3556437
3556439
3556440
3556443
3556444
3556445
3556447
3556451
3556452
3556453
56339
7977749
A_33_P3449397
GE82484
GO:0000398
GO:0001510
GO:0001734
GO:0002181
GO:0002376
GO:0003723
GO:0003729
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005794
GO:0005829
GO:0006325
GO:0006382
GO:0006397
GO:0006402
GO:0006974
GO:0007155
GO:0007283
GO:0007623
GO:0008168
GO:0008173
GO:0008757
GO:0009048
GO:0009451
GO:0016071
GO:0016422
GO:0016604
GO:0016607
GO:0016740
GO:0019827
GO:0021861
GO:0022414
GO:0023052
GO:0030154
GO:0031047
GO:0031053
GO:0032259
GO:0034644
GO:0036396
GO:0042063
GO:0043226
GO:0043414
GO:0045087
GO:0045580
GO:0045727
GO:0045746
GO:0046982
GO:0048477
GO:0048511
GO:0048856
GO:0051445
GO:0060339
GO:0061157
GO:0080009
GO:0098508
GO:0098542
GO:0140098
GO:1902036
GO:1903679
GO:1904047
HMNXSV003009934
Hs.268149.1.A1_3p_a_at
ILMN_1655635
PH_hs_0022798
TC14000922.hg
g12804482_3p_a_at
Participates
as a component of
mRNA (N6-adenosine)-methyltransferase [nucleoplasm] (Homo sapiens)
Inferred To
mettl3 [nucleoplasm]
(Xenopus tropicalis)
METTL3 [nucleoplasm]
(Bos taurus)
METTL3 [nucleoplasm]
(Canis familiaris)
METTL3 [nucleoplasm]
(Drosophila melanogaster)
METTL3 [nucleoplasm]
(Gallus gallus)
METTL3 [nucleoplasm]
(Mus musculus)
METTL3 [nucleoplasm]
(Plasmodium falciparum)
METTL3 [nucleoplasm]
(Sus scrofa)
Mettl3 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_062826.2
Guide to Pharmacology - Targets
3181
OpenTargets
ENSG00000165819
GeneCards
Q86U44
HPA
ENSG00000165819-METTL3
Ensembl
ENST00000298717
,
ENSG00000165819
,
ENSP00000298717
PRO
Q86U44
Pharos - Targets
Q86U44
HMDB Protein
HMDBP00429
PDB
5K7U
,
6TTW
,
7OQO
,
6TTX
,
7OEK
,
6TTV
,
7OEJ
,
7O09
,
7NID
,
7O28
,
5K7W
,
7OEL
,
7O27
,
7NIA
,
6TTP
,
7OED
,
6TTT
,
7OEI
,
7NI8
,
5YZ9
,
5K7M
,
7NHV
,
7O0R
,
7O2I
,
6Y4G
,
7O0Q
,
7O2H
,
7O0P
,
8BN8
,
7NHI
,
7O29
,
5L6E
,
7O0M
,
5L6D
,
7O0L
,
7NI9
,
7OQL
,
6TU1
,
5TEY
,
7OEM
,
7RX6
,
7OQP
,
7O2X
,
7OEF
,
7ACD
,
7OEE
,
7O08
,
7OEH
,
7OEG
,
7NI7
,
5IL2
,
7NHH
,
5IL0
,
7NHG
,
7O2F
,
5IL1
,
7NHJ
,
7RX8
,
7RX7
,
7O2E
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