SRSF1 [nucleoplasm]

Stable Identifier
R-HSA-72031
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SF2/ASF/SFRS1, Splicing factor, arginine/serine-rich 1 (pre-mRNA splicing factor SF2, P33 subunit) (Alternative splicing factor ASF-1), Splicing factor, arginine/serine-rich 1, pre-mRNA splicing factor SF2, P33 subunit, Alternative splicing factor ASF-1
Locations in the PathwayBrowser for interactor UniProt:P61326 MAGOH
Expand all
External Reference Information
External Reference
UniProt:Q07955 SRSF1
Gene Names
SRSF1, ASF, SF2, SF2P33, SFRS1, OK/SW-cl.3
Chain
initiator methionine:1, chain:2-248
Reference Genes
BioGPS Gene:6426 SRSF1
COSMIC (genes):SRSF1 SRSF1
CTD Gene:6426 SRSF1
dbSNP Gene:6426 SRSF1
ENSEMBL:ENSG00000136450 SRSF1
HGNC:10780 SRSF1
KEGG Gene (Homo sapiens):6426 SRSF1
Monarch:6426 SRSF1
NCBI Gene:6426 SRSF1
OMIM:600812 SRSF1
UCSC:Q07955 SRSF1
Reference Transcript
Other Identifiers
0003610358
11727811_a_at
11727812_s_at
11727813_a_at
11743269_a_at
11747684_a_at
11758600_s_at
13073
16846993
1X4A
201741_3p_x_at
201741_x_at
201742_x_at
208863_s_at
211784_s_at
227164_at
2M7S
2M8D
2O3D
36098_at
36099_at
3764113
3764114
3764115
3764116
3764117
3764118
3764119
3764120
3764121
3764122
3764123
3764124
3764125
3764126
3764127
3764128
3764129
3764130
3764131
3764136
3764138
3764139
3764140
3764141
3BEG
46035_at
4C0O
53598_s_at
53602_r_at
60888_r_at
61301
6426
8016898
91177_s_at
A_23_P49517
A_23_P49521
A_24_P921933
AAA03476
AAA35564
AAA35565
AAH10264
AAH33785
AB062124
AK312781
BAB93456
BAG35644
BC010264
BC033785
CAB013073
CCDS11600
CCDS58580
CH471109
EAW94485
EAW94486
ENSG00000136450
ENSP00000258962
ENSP00000462215
ENSP00000463223
ENST00000258962
ENST00000258962.4
ENST00000581979
ENST00000581979.5
ENST00000582730
ENST00000582730.6
EntrezGene:6426
EntrezGene:SRSF1
g13544106_3p_s_at
g5902075_3p_s_at
GE58054
GE86679
GE88490
GO:0000380
GO:0000381
GO:0000395
GO:0000398
GO:0003674
GO:0003676
GO:0003723
GO:0003729
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005681
GO:0005737
GO:0006376
GO:0006397
GO:0006405
GO:0006406
GO:0006810
GO:0006913
GO:0008150
GO:0008380
GO:0016607
GO:0019899
GO:0022607
GO:0022618
GO:0031124
GO:0032991
GO:0034641
GO:0035145
GO:0043226
GO:0044547
GO:0045292
GO:0051028
GO:0065003
GO:0071013
HGNC:10780
HPA061301
Hs.44949.0.A1_3p_at
Hs.73737.0.S2_3p_s_at
ILMN_1795341
IPR000504
IPR012677
IPR029538
IPR034520
IPR035979
J3KSW7
J3KTL2
J3QQV5
M69040
M72709
MIM:600812
NM_001078166
NM_006924
NP_001071634
NP_008855
NR_034041
PF00076
PH_hs_0022174
SM00360
SRSF1
SRSF1-201
SRSF1-204
SRSF1-205
TC17001724.hg
TC17002724.hg
UPI0000001220
UPI000017A383
XR_429911
Participant Of
hasComponent
input
output
Inferred To
SRSF1 [nucleoplasm] (Bos taurus)
SRSF1 [nucleoplasm] (Caenorhabditis elegans)
SRSF1 [nucleoplasm] (Canis familiaris)
SRSF1 [nucleoplasm] (Danio rerio)
SRSF1 [nucleoplasm] (Drosophila melanogaster)
SRSF1 [nucleoplasm] (Gallus gallus)
SRSF1 [nucleoplasm] (Mus musculus)
SRSF1 [nucleoplasm] (Plasmodium falciparum)
SRSF1 [nucleoplasm] (Rattus norvegicus)
SRSF1 [nucleoplasm] (Schizosaccharomyces pombe)
SRSF1 [nucleoplasm] (Sus scrofa)
SRSF1 [nucleoplasm] (Xenopus tropicalis)
Ghost homologue of SRSF1 [nucleoplasm] (Dictyostelium discoideum)
Cross References
RefSeq
OpenTargets
GeneCards
PRO
PDB
Interactors (61)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9UBU9 NXF1  2 0.76 5
 UniProt:Q96SB4 SRPK1      0.667 3
 UniProt:P38919 EIF4A3  2 0.662 7
 UniProt:Q14684 RRP1B      0.649 6
 UniProt:Q01081 U2AF1  1 0.646 4
 UniProt:O70551 SRPK1      0.639 5
 IntAct:EBI-17172839 LNCRN      0.602 7
 UniProt:P23511 NFYA  1 0.599 5
 UniProt:Q15287 RNPS1  2 0.573 2
 UniProt:P61981 YWHAG  1 0.564 2
 UniProt:P08621 SNRNP70  1 0.524 3
 UniProt:O54781 SRPK2      0.524 3
 UniProt:P51858 HDGF  1 0.512 4
 UniProt:Q86X95 CIR1      0.508 3
 UniProt:P03211 EBNA1      0.508 2
 UniProt:O00463 TRAF5      0.499 2
 UniProt:Q15696 ZRSR2  1 0.488 2
 UniProt:P62995 TRA2B  1 0.488 2
 UniProt:P06921 VE2      0.488 2
 UniProt:P49759-3 CLK1      0.488 2
 IntAct:EBI-20986914 MRNA      0.462 2
 IntAct:EBI-16421993 MRNA      0.462 2
 IntAct:EBI-20986916 MRNA      0.462 2
 IntAct:EBI-21196637 MRNA      0.462 2
 IntAct:EBI-21003641 MRNA      0.462 2
 UniProt:P03372 ESR1  8 0.462 2
 IntAct:EBI-21196643 MRNA      0.462 2
 IntAct:EBI-20978533 MRNA      0.462 2
 IntAct:EBI-21196681 MRNA      0.462 2
 IntAct:EBI-20986867 MRNA      0.462 2
 IntAct:EBI-21196806 MRNA      0.462 2
 UniProt:P11387 TOP1  2 0.462 3
 UniProt:P61326 MAGOH  1 0.462 2
 IntAct:EBI-21196689 MRNA      0.462 2
 IntAct:EBI-20987118 MRNA      0.462 2
 IntAct:EBI-20987111 MRNA      0.462 2
 IntAct:EBI-21196652 MRNA      0.462 2
 IntAct:EBI-20978528 MRNA      0.462 2
 IntAct:EBI-21196816 MRNA      0.462 2
 IntAct:EBI-20978553 MRNA      0.462 2
 IntAct:EBI-20986938 MRNA      0.462 2
 IntAct:EBI-20987101 MRNA      0.462 2
 IntAct:EBI-21003667 MRNA      0.462 2
 IntAct:EBI-21196665 MRNA      0.462 2
 UniProt:P51957-2 NEK4      0.462 2
 IntAct:EBI-21196622 MRNA      0.462 2
 IntAct:EBI-20986925 MRNA      0.462 2
 IntAct:EBI-21196628 MRNA      0.462 2
 IntAct:EBI-21196823 MRNA      0.462 2
 IntAct:EBI-21003674 MRNA      0.462 2
 IntAct:EBI-20986929 MRNA      0.462 2
 IntAct:EBI-16419307 MRA      0.462 2
 IntAct:EBI-20986882 MRNA      0.462 2
 IntAct:EBI-21003634 MRNA      0.462 2
 IntAct:EBI-21196829 MRNA      0.462 2
 IntAct:EBI-16412875 MRNA      0.462 2
 IntAct:EBI-20986921 MRNA      0.462 2
 IntAct:EBI-21196797 MRNA      0.462 2
 IntAct:EBI-21196675 MRNA      0.462 2
 IntAct:EBI-21196671 MRNA      0.462 2
 IntAct:EBI-21196673 MRNA      0.462 2