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SRSF7 [nucleoplasm]
Stable Identifier
R-HSA-72029
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SR7/ 9G8 protein, Splicing factor, arginine/serine-rich 7, Splicing factor 9G8
Locations in the PathwayBrowser for interactor UniProt:Q8WVS4 DYNC2I1
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Transport of Mature Transcript to Cytoplasm (Homo sapiens)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Homo sapiens)
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
SRSF7 [nucleoplasm] (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Minor Pathway (Homo sapiens)
Formation of AT-AC A complex (Homo sapiens)
SRSF7 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q16629 SRSF7
Gene Names
SRSF7, SFRS7
Chain
chain:1-238
Reference Genes
BioGPS Gene:6432 SRSF7
COSMIC (genes):SRSF7 SRSF7
CTD Gene:6432 SRSF7
dbSNP Gene:6432 SRSF7
ENSEMBL:ENSG00000115875 SRSF7
HGNC:10789 SRSF7
KEGG:hsa:6432 SRSF7
Monarch:6432 SRSF7
NCBI Gene:6432 SRSF7
OMIM:600572 SRSF7
UCSC:Q16629 SRSF7
Reference Transcript
RefSeq:NM_001195446.1 SRSF7
RefSeq:NM_001031684.2 SRSF7
Other Identifiers
11717293_x_at
11717294_a_at
11751602_a_at
11751603_x_at
16896650
201129_PM_at
201129_at
213649_PM_at
213649_at
214141_3p_x_at
214141_PM_x_at
214141_x_at
2548954
2548971
2548972
2548973
2548976
2548978
2548979
2548980
2548981
2548982
2548984
2548985
2548986
2548987
2548988
2548989
2548990
2548991
2548992
2548993
2548995
2548998
2548999
2549000
2549001
2549003
32165_at
6432
8051622
A_23_P39704
A_24_P222911
A_33_P3305840
GE62636
GO:0000398
GO:0003676
GO:0003723
GO:0003729
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0006397
GO:0008270
GO:0008380
GO:0016071
GO:0016607
GO:0019904
GO:0043226
GO:0046872
GO:0048025
GO:0051028
GO:0070062
GO:1990830
HMNXSV003018006
Hs.184167.1.S1_3p_s_at
Hs.184167.2.A1_3p_at
ILMN_1778836
L41887_rna1_at
PH_hs_0023688
TC02001757.hg
g6002475_3p_s_at
g6857827_3p_at
p27362
Participates
as a component of
post exon ligation complex [nucleoplasm] (Homo sapiens)
ATAC C Complex with lariat containing 5'-end cleaved mRNA [nucleoplasm] (Homo sapiens)
ATAC C Complex [nucleoplasm] (Homo sapiens)
ATAC A Complex [nucleoplasm] (Homo sapiens)
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
Spliced mRNP [nucleoplasm] (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Homo sapiens)
as an input of
Formation of AT-AC A complex (Homo sapiens)
as a member of
shuttling SRSFs [nucleoplasm] (Homo sapiens)
as an output of
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
Inferred To
rsp-6 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of SRSF7 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of SRSF7 [nucleoplasm]
(Xenopus tropicalis)
Srsf7 [nucleoplasm]
(Mus musculus)
Srsf7 [nucleoplasm]
(Rattus norvegicus)
srsf7b [nucleoplasm]
(Danio rerio)
x16 [nucleoplasm]
(Drosophila melanogaster)
SRSF7 [nucleoplasm]
(Bos taurus)
SRSF7 [nucleoplasm]
(Canis familiaris)
SRSF7 [nucleoplasm]
(Gallus gallus)
SRSF7 [nucleoplasm]
(Schizosaccharomyces pombe)
SRSF7 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_001026854.1
,
NP_001182375.1
OpenTargets
ENSG00000115875
ENSEMBL
ENSP00000402264
,
ENST00000313117
,
ENSP00000402544
,
ENST00000443213
,
ENST00000446327
,
ENSP00000398159
,
ENST00000431066
,
ENSP00000325905
HPA
ENSG00000115875-SRSF7
PRO
Q16629
Pharos - Targets
Q16629
GlyGen
Q16629
PDB
2HVZ
Interactors (55)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y383 LC7L2
0.781
7
UniProt:O00560 SDCBP
3
SDCBP [cytosol]
(R-HSA-373639)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [extracellular region]
(R-HSA-6806206)
0.718
6
UniProt:Q9UBU9 NXF1
2
NXF1 [nucleoplasm]
(R-HSA-111690)
NXF1 [cytosol]
(R-HSA-156481)
0.667
4
UniProt:Q15287 RNPS1
2
RNPS1 [cytosol]
(R-HSA-159256)
RNPS1 [nucleoplasm]
(R-HSA-156778)
0.666
4
UniProt:Q7Z6E9 RBBP6
1
RBBP6 [cytosol]
(R-HSA-8850895)
0.655
4
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.642
3
UniProt:Q96SB4 SRPK1
2
SRPK1 [nucleoplasm]
(R-HSA-9821984)
SRPK1 [cytosol]
(R-HSA-9729349)
0.642
3
UniProt:Q53F19 NCBP3
0.615
4
UniProt:Q86VM9 ZCH18
0.615
6
UniProt:Q00534 CDK6
3
p-T177-CDK6 [nucleoplasm]
(R-HSA-69628)
CDK6 [nucleoplasm]
(R-HSA-141283)
CDK6 [cytosol]
(R-HSA-68336)
0.571
2
UniProt:Q8NAV1 PRPF38A
1
PRPF38A [nucleoplasm]
(R-HSA-8867897)
0.556
3
UniProt:Q9NQ29-3 LUC7L
0.556
3
UniProt:P49759-3 CLK1
0.556
3
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.527
2
UniProt:P38919 EIF4A3
2
EIF4A3 [nucleoplasm]
(R-HSA-8849149)
EIF4A3 [cytosol]
(R-HSA-927868)
0.527
2
UniProt:Q99459 CDC5L
1
CDC5L [nucleoplasm]
(R-HSA-5420887)
0.527
2
UniProt:P49761 CLK3
0.527
2
UniProt:Q8WVS4 DYNC2I1
2
WDR60 [ciliary tip]
(R-HSA-5625409)
WDR60 [cilium]
(R-HSA-5624903)
0.508
2
UniProt:Q9JKL7 SREK1
0.499
3
UniProt:Q9NYF8 BCLF1
0.483
2
UniProt:Q9C0J8 WDR33
1
WDR33 [nucleoplasm]
(R-HSA-8938784)
0.483
2
UniProt:O15226 NKRF
0.483
2
UniProt:Q9NUL3 STAU2
0.483
2
UniProt:Q7L014 DDX46
1
DDX46 [nucleoplasm]
(R-HSA-5688096)
0.483
2
UniProt:Q9H7N4 SFR19
0.483
2
UniProt:Q8IX01 SUGP2
0.483
2
UniProt:Q92665 MRPS31
1
MRPS31 [mitochondrial inner membrane]
(R-HSA-5368198)
0.483
2
UniProt:Q6PJT7 ZC3HE
0.483
2
UniProt:Q9NYY8 FASTKD2
1
FASTKD2 [mitochondrial matrix]
(R-HSA-9837146)
0.483
2
UniProt:Q6PKG0 LARP1
1
LARP1 [cytosol]
(R-HSA-9760421)
0.483
2
UniProt:Q9Y2W1 THRAP3
1
THRAP3 [nucleoplasm]
(R-HSA-8932115)
0.483
2
UniProt:Q9BXP5 SRRT
1
SRRT [nucleoplasm]
(R-HSA-6814858)
0.483
2
UniProt:Q8WUD4 CCDC12
1
CCDC12 [nucleoplasm]
(R-HSA-9769561)
0.483
2
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.483
2
UniProt:Q9H2U1 DHX36
1
DHX36 [cytosol]
(R-HSA-3134862)
0.483
2
UniProt:Q13616 CUL1
3
CUL1 [cytosol]
(R-HSA-174230)
CUL1 [nucleoplasm]
(R-HSA-187551)
G76-NEDD8-K720-CUL1 [cytosol]
(R-HSA-8952519)
0.483
2
UniProt:Q13627 DYRK1A
1
DYRK1A [nucleoplasm]
(R-HSA-1362267)
0.483
2
UniProt:Q14562 DHX8
1
DHX8 [nucleoplasm]
(R-HSA-5688092)
0.483
2
UniProt:Q14498 RBM39
1
RBM39 [nucleoplasm]
(R-HSA-9770254)
0.483
2
UniProt:O95639 CPSF4
1
CPSF4 [nucleoplasm]
(R-HSA-169104)
0.483
2
UniProt:Q49A26 GLYR1
0.483
2
UniProt:Q96KR1 ZFR
0.483
2
UniProt:O15042 U2SURP
1
U2SURP [nucleoplasm]
(R-HSA-8865950)
0.483
2
UniProt:Q9H307 PNN
1
PNN [nucleoplasm]
(R-HSA-9770779)
0.483
2
UniProt:Q96MU7 YTDC1
0.483
2
UniProt:Q8IUH3 RBM45
0.483
2
UniProt:Q9HCD5 NCOA5
0.483
2
UniProt:Q6NZY4 ZCCHC8
1
ZCCHC8 [nucleoplasm]
(R-HSA-8985573)
0.483
2
UniProt:Q9NZB2 F120A
0.483
2
UniProt:Q9UH17 APOBEC3B
1
APOBEC3B [nucleoplasm]
(R-HSA-8875003)
0.483
2
UniProt:Q9HCS7 XAB2
1
XAB2 [nucleoplasm]
(R-HSA-67411)
0.483
2
UniProt:Q8IWX8 CHERP
1
CHERP [nucleoplasm]
(R-HSA-8865901)
0.483
2
UniProt:Q96EY7 PTCD3
1
PTCD3 [mitochondrial inner membrane]
(R-HSA-5368165)
0.483
2
UniProt:Q14966 ZNF638
1
ZNF638 [nucleoplasm]
(R-HSA-8939429)
0.483
2
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.462
2
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