Reactome | PABPN1 [nucleoplasm]

PABPN1 [nucleoplasm]

Stable Identifier

R-HSA-72008

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Poly(A)-binding protein II, PAB II

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Locations in the PathwayBrowser for interactor UniProt:Q13573%20SNW1

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External Reference Information

External Reference

UniProt:Q86U42 PABPN1

Gene Names

PABPN1, PAB2, PABP2

Chain

initiator methionine:, chain:2-306

Reference Genes

BioGPS Gene:8106 PABPN1

COSMIC (genes):PABPN1 PABPN1

CTD Gene:8106 PABPN1

dbSNP Gene:8106 PABPN1

ENSEMBL:ENSG00000100836 PABPN1

ENSEMBL_homo_sapiens_GENE:ENSG00000100836.11 PABPN1

HGNC:8565 PABPN1

KEGG Gene (Homo sapiens):8106 PABPN1

Monarch:8106 PABPN1

NCBI Gene:8106 PABPN1

OMIM:602279 PABPN1

UCSC:Q86U42 PABPN1

Reference Transcript

RefSeq:NM_004643.3 PABPN1

Other Identifiers

11718844_s_at

11718845_a_at

11763165_at

201544_3p_x_at

201544_PM_x_at

201544_x_at

201545_PM_s_at

201545_s_at

213046_PM_at

213046_at

3529085

3529088

3529090

3529092

3529094

3529096

3529097

3529098

3529099

3529100

3529101

3529102

3529103

3840483

39050_at

7973384

8106

A_14_P111774

A_23_P128828

GE79123

GO:0000165

GO:0003012

GO:0003676

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0006396

GO:0006397

GO:0006913

GO:0006936

GO:0008143

GO:0016071

GO:0016607

GO:0016973

GO:0023052

GO:0042405

GO:0043226

GO:0070063

GO:0071222

GO:1904247

GO:1990904

HMNXSV003039577

Hs.117176.0.S1_3p_a_at

Hs.117176.0.S1_3p_x_at

Hs.117176.1.S1_3p_at

ILMN_1759154

PH_hs_0006427

TC14002292.hg

g4758875_3p_a_at

Participates

as an input of

as a component of

as an output of

Other forms of this molecule

PABPN1 [cytosol]

Inferred To

Ghost homologue of PABPN1 [nucleoplasm] (Canis familiaris)

zgc:85979 [nucleoplasm] (Danio rerio)

Homologues of PABPN1 [nucleoplasm] (Bos taurus)

PABPN1 [nucleoplasm] (Bos taurus)

PABPN1 [nucleoplasm] (Gallus gallus)

PABPN1 [nucleoplasm] (Sus scrofa)

Pabp2 [nucleoplasm] (Drosophila melanogaster)

Pabpn1 [nucleoplasm] (Mus musculus)

Pabpn1 [nucleoplasm] (Rattus norvegicus)

pabp-2 [nucleoplasm] (Caenorhabditis elegans)

pabpn1 [nucleoplasm] (Dictyostelium discoideum)

pabpn1 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_004634.1

OpenTargets

ENSG00000100836

HPA

ENSG00000100836-PABPN1

GeneCards

Q86U42

Ensembl

ENSG00000100836, ENST00000397276, ENSP00000380446, ENSP00000216727, ENST00000216727

PRO

Q86U42

Pharos - Targets

Q86U42

Orphanet

16602

HMDB Protein

HMDBP08498

PDB

3B4M, 3UCG, 3B4D

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.696	5
UniProt:P67809 YBX1	5	p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) p-S32,S36-YBX1 [cytosol] (R-HSA-9736837) YBX1 [cytosol] (R-HSA-9736840) YBX1 [nucleoplasm] (R-HSA-72041) YBX1 [extracellular region] (R-HSA-9017791)	0.558	4
UniProt:Q53F19 NCBP3			0.527	5
UniProt:Q09161 NCBP1	2	NCBP1 [nucleoplasm] (R-HSA-51469) NCBP1 [cytosol] (R-HSA-162459)	0.527	6
UniProt:P11940 PABPC1	1	PABPC1 [cytosol] (R-HSA-156803)	0.499	2

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