Reactome | SF3B5 [nucleoplasm]

SF3B5 [nucleoplasm]

Stable Identifier

R-HSA-71979

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Splicing factor 3B subunit 5, SF3b5, Pre-mRNA splicing factor SF3b 10 kDa subunit

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BWJ5 SF3B5

Gene Names

SF3B5, SF3B10

Chain

initiator methionine:, chain:2-86

Reference Genes

BioGPS Gene:83443 SF3B5

COSMIC (genes):SF3B5 SF3B5

CTD Gene:83443 SF3B5

dbSNP Gene:83443 SF3B5

ENSEMBL:ENSG00000169976 SF3B5

HGNC:21083 SF3B5

KEGG:hsa:83443 SF3B5

Monarch:83443 SF3B5

NCBI Gene:83443 SF3B5

OMIM:617847 SF3B5

UCSC:Q9BWJ5 SF3B5

Reference Transcript

RefSeq:NM_031287.2 SF3B5

Other Identifiers

11715605_s_at

11757428_a_at

17024418

221263_PM_s_at

221263_s_at

2977691

2977692

2977693

48858_at

8130003

83443

A_23_P19576

GE79566

GO:0000124

GO:0000398

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005684

GO:0005686

GO:0005689

GO:0006282

GO:0006355

GO:0006397

GO:0008380

GO:0016071

GO:0043226

GO:0043484

GO:0045893

GO:0065003

GO:0071005

GO:0071011

GO:1903241

GO:1990935

HMNXSV003000812

ILMN_1689389

PH_hs_0006091

TC06002191.hg

g13775199_3p_s_at

Participates

as a component of

SF3B [nucleoplasm] (Homo sapiens)

Inferred To

SF3B5 [nucleoplasm] (Bos taurus)

SF3B5 [nucleoplasm] (Canis familiaris)

SF3B5 [nucleoplasm] (Gallus gallus)

SF3B5 [nucleoplasm] (Plasmodium falciparum)

SF3B5 [nucleoplasm] (Schizosaccharomyces pombe)

SF3B5 [nucleoplasm] (Sus scrofa)

Ghost homologue of SF3B5 [nucleoplasm] (Caenorhabditis elegans)

Sf3b5 [nucleoplasm] (Drosophila melanogaster)

Sf3b5 [nucleoplasm] (Mus musculus)

Sf3b5 [nucleoplasm] (Rattus norvegicus)

sf3b5 [nucleoplasm] (Danio rerio)

sf3b5 [nucleoplasm] (Dictyostelium discoideum)

sf3b5 [nucleoplasm] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000169976

ENSEMBL

ENST00000367569, ENSG00000169976, ENSP00000356541

HPA

ENSG00000169976-SF3B5

GeneCards

SF3B5

PRO

Q9BWJ5

Pharos - Targets

Q9BWJ5

GlyGen

Q9BWJ5

PDB

7KTS, 8QZS, 8QXD, 6Y50, 7Q4O, 7Q3L, 6FF7, 6QX9, 8I0U, 8I0T, 6EN4, 8I0P, 5IFE, 8H6E, 5Z57, 7B0I, 7EVN, 8R08, 7OMF, 6AH0, 8H6K, 7B9C, 7ONB, 8QO9, 8R0A, 7ABH, 6FF4, 8I0V, 5Z58, 5O9Z, 7DVQ, 6Y5Q, 7ABG, 8HK1, 8I0S, 7QTT, 7OPI, 8CH6, 7ABI, 8I0R, 8H7G, 7VPX, 5Z56, 7B91, 7Q4P, 7B92, 5ZYA, 8R0B, 8Y7E, 8H6L, 8H6J, 8RM5, 7EVO, 8R09

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.643	3
UniProt:Q96FJ0 STAMBPL1	1	STAMBPL1 [cytosol] (R-HSA-6783264)	0.556	3
UniProt:P62304 SNRPE	2	SNRPE [cytosol] (R-HSA-191782) SNRPE [nucleoplasm] (R-HSA-71905)	0.527	2
UniProt:P62306 SNRPF	2	SNRPF [cytosol] (R-HSA-191852) SNRPF [nucleoplasm] (R-HSA-71907)	0.527	3
UniProt:P14678 SNRPB	4	2xMe-SNRPB [cytosol] (R-HSA-192218) SNRPB [cytosol] (R-HSA-191798) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [nucleoplasm] (R-HSA-71896)	0.527	2