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LSM2 [nucleoplasm]
Stable Identifier
R-HSA-71894
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm2, Small nuclear ribonuclear protein D homolog, G7b, SnRNP core SM-like protein SM-x5
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)
U4 snRNP:U6 snRNP complex [nucleoplasm] (Homo sapiens)
U6 snRNP [nucleoplasm] (Homo sapiens)
LSM2-8 complex [nucleoplasm] (Homo sapiens)
LSM2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
LSM2-8 complex [nucleoplasm] (Homo sapiens)
LSM2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)
U4 snRNP:U6 snRNP complex [nucleoplasm] (Homo sapiens)
U6 snRNP [nucleoplasm] (Homo sapiens)
LSM2-8 complex [nucleoplasm] (Homo sapiens)
LSM2 [nucleoplasm] (Homo sapiens)
U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)
U4 snRNP:U6 snRNP complex [nucleoplasm] (Homo sapiens)
U6 snRNP [nucleoplasm] (Homo sapiens)
LSM2-8 complex [nucleoplasm] (Homo sapiens)
LSM2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y333 LSM2
Gene Names
LSM2, C6orf28, G7B
Chain
chain:1-95
Reference Genes
BioGPS Gene:57819 LSM2
COSMIC (genes):LSM2 LSM2
CTD Gene:57819 LSM2
dbSNP Gene:57819 LSM2
ENSEMBL:ENSG00000204392 LSM2
HGNC:13940 LSM2
KEGG:hsa:57819 LSM2
Monarch:57819 LSM2
NCBI Gene:57819 LSM2
OMIM:607282 LSM2
UCSC:Q9Y333 LSM2
Reference Transcript
RefSeq:NM_021177.4 LSM2
Other Identifiers
11717390_a_at
17017476
17026855
17029328
17032114
17036832
17039565
209449_PM_at
209449_at
2949432
2949433
2949434
2949435
2949436
2949437
2949439
2949442
2949443
2949444
41375_at
57819
8125125
8178641
8179839
A_23_P59153
A_33_P3261625
GE55281
GO:0000244
GO:0000398
GO:0000932
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005688
GO:0005737
GO:0005829
GO:0006397
GO:0006402
GO:0008380
GO:0016071
GO:0017070
GO:0031267
GO:0043226
GO:0046540
GO:0065003
GO:0071005
GO:0071011
GO:0071013
GO:0120115
GO:1990726
HMNXSV003014418
ILMN_2070300
PH_hs_0005719
TC06001545.hg
TC6_apd_hap1000086.hg
TC6_cox_hap2000172.hg
TC6_dbb_hap3000161.hg
TC6_mcf_hap5000149.hg
TC6_qbl_hap6000162.hg
g11225486_3p_at
Participates
as a component of
LSM2-8 complex [nucleoplasm] (Homo sapiens)
Other forms of this molecule
LSM2 [cytosol]
Inferred To
Ghost homologue of LSM2 [nucleoplasm]
(Gallus gallus)
Lsm2 [nucleoplasm]
(Mus musculus)
Dmel\CG10418 [nucleoplasm]
(Drosophila melanogaster)
gut-2 [nucleoplasm]
(Caenorhabditis elegans)
lsm2 [nucleoplasm]
(Dictyostelium discoideum)
lsm2 [nucleoplasm]
(Schizosaccharomyces pombe)
lsm2 [nucleoplasm]
(Xenopus tropicalis)
LSM2 [nucleoplasm]
(Bos taurus)
LSM2 [nucleoplasm]
(Canis familiaris)
LSM2 [nucleoplasm]
(Plasmodium falciparum)
LSM2 [nucleoplasm]
(Rattus norvegicus)
LSM2 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_067000.1
OpenTargets
ENSG00000204392
ENSEMBL
ENSP00000403345
,
ENSP00000406280
,
ENST00000383391
,
ENST00000424975
,
ENST00000432122
,
ENST00000434125
,
ENSP00000414006
,
ENSP00000364813
,
ENSP00000414634
,
ENSP00000372883
,
ENST00000375661
,
ENST00000455705
HPA
ENSG00000204392-LSM2
PRO
Q9Y333
Pharos - Targets
Q9Y333
GlyGen
Q9Y333
PDB
8QO9
,
8R09
,
8R0A
,
8R08
,
8RM5
,
8QZS
,
3JCR
,
8H6K
,
8QXD
,
6AH0
,
8H6L
,
8H6J
,
8R0B
,
6AHD
,
7ABG
,
6QW6
,
5O9Z
,
6QX9
,
8H6E
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62316 SNRPD2
2
SNRPD2 [cytosol]
(R-HSA-191810)
SNRPD2 [nucleoplasm]
(R-HSA-71901)
0.748
4
UniProt:P62304 SNRPE
2
SNRPE [cytosol]
(R-HSA-191782)
SNRPE [nucleoplasm]
(R-HSA-71905)
0.745
5
UniProt:P62306 SNRPF
2
SNRPF [cytosol]
(R-HSA-191852)
SNRPF [nucleoplasm]
(R-HSA-71907)
0.643
3
UniProt:Q8N9N5 BANP
1
BANP [nucleoplasm]
(R-HSA-3221973)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:P31689 DNAJA1
2
SOH-C149,C150-DNAJA1 [cytosol]
(R-HSA-9857072)
DNAJA1 [cytosol]
(R-HSA-3371544)
0.553
2
UniProt:P14678 SNRPB
4
2xMe-SNRPB [cytosol]
(R-HSA-192218)
SNRPB [cytosol]
(R-HSA-191798)
Me2-R108,R112-SNRPB [nucleoplasm]
(R-HSA-192213)
SNRPB [nucleoplasm]
(R-HSA-71896)
0.547
2
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