Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+

Stable Identifier
R-HSA-71783
Type
Reaction
Species
Homo sapiens
Compartment
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Mitochondrial malate dehydrogenase catalyzes the reversible reaction of oxaloacetate and NADH + H+ to form malate and NAD+ (Luo et al. 2006). Unpublished crystallographic data indicate that the protein is a dimer (PDB 3E04).

Literature References
PubMed ID Title Journal Year
16740313 An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates

Liu, J, Wang, X, Long, J, Luo, C

J Biochem Biophys Methods 2006
Participants
Participates
Catalyst Activity

L-malate dehydrogenase activity of MDH2 dimer [mitochondrial matrix]

Orthologous Events
Cross References
Rhea
Reviewed
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