ALDH2 (aldehyde dehydrogenase) in the mitochondrial matrix catalyzes the reaction of acetaldehyde and NAD+ to form acetate and NADH + H+ (Greenfield and Pietruszko 1977; Hempel et al. 1985). The active form of the enzyme is a tetramer (Ni et al. 1999).
Hempel, J, Kaiser, R, Jornvall, H
Ni, L, Zhou, J, Hurley, TD, Weiner, H
Greenfield, NJ, Pietruszko, R
aldehyde dehydrogenase (NAD+) activity of ALDH2 tetramer [mitochondrial matrix]
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