PXLP-SHMT1 [cytosol]

Stable Identifier
R-HSA-71242
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SHMT1, serine hydroxymethyltransferase, glycine hydroxymethyltransferase, Serine methylase
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P34896 SHMT1
Gene Names
SHMT1
Chain
chain:1-483
Reference Genes
BioGPS Gene:6470 SHMT1
COSMIC (genes):SHMT1 SHMT1
CTD Gene:6470 SHMT1
dbSNP Gene:6470 SHMT1
ENSEMBL:ENSG00000176974 SHMT1
ENSEMBL_homo_sapiens_GENE:ENSG00000176974 SHMT1
HGNC:10850 SHMT1
KEGG Gene (Homo sapiens):6470 SHMT1
Monarch:6470 SHMT1
NCBI Gene:6470 SHMT1
OMIM:182144 SHMT1
UCSC:P34896 SHMT1
Reference Transcript
Other Identifiers
0000380156
0000380341
00260+2.1.2.1
00460+2.1.2.1
00630+2.1.2.1
00670+2.1.2.1
00680+2.1.2.1
11733969_a_at
11740366_a_at
11751011_x_at
11756209_x_at
16842103
1BJ4
209980_s_at
224954_at
23314
2409444
2409446
2409449
2409450
34738_at
3748324
3748325
3748326
3748327
3748330
3748331
3748333
3748334
3748335
3748336
3748338
3748340
3748342
3748347
3748348
3748353
6470
712_s_at
78803_at
8013243
A_23_P502654
A_24_P205364
AAA36018
AAA36019
AAA36020
AAA63257
AAH07979
AAH22874
AAH38598
BAG60641
CAB54838
CAB54839
CAB54840
CCDS11196
CCDS11197
CCDS62112
EAW55637
EAW55640
EAW55641
ENSG00000176974
ENSP00000318805
ENSP00000318868
ENSP00000345881
ENST00000316694
ENST00000352886
ENST00000354098
EntrezGene:6470
g438633_3p_a_at
GE81357
GO:0000900
GO:0003674
GO:0003723
GO:0003729
GO:0003824
GO:0004372
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0006231
GO:0006412
GO:0006520
GO:0006544
GO:0006545
GO:0006563
GO:0006565
GO:0006730
GO:0008150
GO:0008270
GO:0008732
GO:0009056
GO:0009058
GO:0009113
GO:0016597
GO:0016740
GO:0016829
GO:0017148
GO:0019264
GO:0022607
GO:0030170
GO:0034641
GO:0035999
GO:0042802
GO:0042803
GO:0043167
GO:0043226
GO:0044281
GO:0045329
GO:0046653
GO:0046655
GO:0048027
GO:0050897
GO:0051186
GO:0051262
GO:0051289
GO:0065003
GO:0070062
GO:0070905
GO:1904482
GO:1990830
HGNC:10850
HPA023314
Hs.8889.1.A2_3p_at
ILMN_1743784
ILMN_1811933
ILMN_2402463
IPR001085
IPR015421
IPR015422
IPR015424
IPR019798
J3KRZ5
L11931_at
MIM:182144
NM_001281786
NM_004169
NM_148918
NP_001268715
NP_004160
NP_683718
PF00464
PH_hs_0029657
SHMT1
SHMT1-201
SHMT1-202
SHMT1-203
TC17001201.hg
TC17002528.hg
uc002gta.5
uc002gtb.5
uc010vxt.3
UPI0000001C71
UPI000002AA9C
UPI00017A769A
XM_005256767
XM_011523992
XM_017024957
XM_017024958
XM_017024959
XM_017024960
XP_005256824
XP_011522294
XP_016880446
XP_016880447
XP_024306656
Participant Of
hasComponent
Inferred To
Homologues of PXLP-SHMT1 [cytosol] (Arabidopsis thaliana)
Homologues of PXLP-SHMT1 [cytosol] (Danio rerio)
Homologues of PXLP-SHMT1 [cytosol] (Dictyostelium discoideum)
Homologues of PXLP-SHMT1 [cytosol] (Drosophila melanogaster)
Homologues of PXLP-SHMT1 [cytosol] (Gallus gallus)
Homologues of PXLP-SHMT1 [cytosol] (Oryza sativa)
Homologues of PXLP-SHMT1 [cytosol] (Saccharomyces cerevisiae)
Homologues of PXLP-SHMT1 [cytosol] (Schizosaccharomyces pombe)
PXLP-SHMT1 [cytosol] (Arabidopsis thaliana)
PXLP-SHMT1 [cytosol] (Bos taurus)
PXLP-SHMT1 [cytosol] (Caenorhabditis elegans)
PXLP-SHMT1 [cytosol] (Canis familiaris)
PXLP-SHMT1 [cytosol] (Danio rerio)
PXLP-SHMT1 [cytosol] (Dictyostelium discoideum)
PXLP-SHMT1 [cytosol] (Drosophila melanogaster)
PXLP-SHMT1 [cytosol] (Gallus gallus)
PXLP-SHMT1 [cytosol] (Mus musculus)
PXLP-SHMT1 [cytosol] (Oryza sativa)
PXLP-SHMT1 [cytosol] (Plasmodium falciparum)
PXLP-SHMT1 [cytosol] (Rattus norvegicus)
PXLP-SHMT1 [cytosol] (Saccharomyces cerevisiae)
PXLP-SHMT1 [cytosol] (Schizosaccharomyces pombe)
PXLP-SHMT1 [cytosol] (Sus scrofa)
PXLP-SHMT1 [cytosol] (Taeniopygia guttata)
PXLP-SHMT1 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
N6-pyridoxal phosphate-L-lysine at 257
Coordinate
257
PsiMod Name
N6-pyridoxal phosphate-L-lysine [MOD:00128]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.
Cross References
RefSeq
OpenTargets
GeneCards
DOCK Blaster
ZINC target
PRO
BRENDA (Homo sapiens)
Orphanet
HMDB Protein
PDB
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P0DMM9 SULT1A3  1 0.556 3