PXLP-SHMT1 [cytosol]

Stable Identifier
R-HSA-71242
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SHMT1, serine hydroxymethyltransferase, glycine hydroxymethyltransferase, Serine methylase
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P34896 SHMT1
Gene Names
SHMT1
Chain
chain:1-483
Reference Genes
BioGPS Gene:6470 SHMT1
COSMIC (genes):SHMT1 SHMT1
CTD Gene:6470 SHMT1
dbSNP Gene:6470 SHMT1
ENSEMBL:ENSG00000176974 SHMT1
ENSEMBL:ENSG00000176974.21 SHMT1
ENSEMBL:ENSG00000284320.3 SHMT1
HGNC:10850 SHMT1
KEGG Gene (Homo sapiens):6470 SHMT1
Monarch:6470 SHMT1
NCBI Gene:6470 SHMT1
OMIM:182144 SHMT1
UCSC:P34896 SHMT1
Reference Transcript
Other Identifiers
0000380156
0000380341
11733969_a_at
11740366_a_at
11751011_x_at
11756209_x_at
16842103
209980_PM_s_at
209980_s_at
224954_PM_at
224954_at
2409444
2409446
2409449
2409450
34738_at
3748322
3748324
3748325
3748326
3748327
3748330
3748331
3748333
3748334
3748335
3748336
3748338
3748340
3748342
3748347
3748348
3748353
6470
712_s_at
78803_at
8013243
A_23_P502654
A_24_P205364
GE81357
GO:0000900
GO:0003674
GO:0003723
GO:0003729
GO:0003824
GO:0004372
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006231
GO:0006520
GO:0006544
GO:0006563
GO:0006565
GO:0006575
GO:0006730
GO:0006766
GO:0008150
GO:0008270
GO:0009113
GO:0016740
GO:0017148
GO:0019264
GO:0030170
GO:0035999
GO:0036094
GO:0042802
GO:0042803
GO:0043167
GO:0043226
GO:0046653
GO:0046655
GO:0048027
GO:0051289
GO:0055086
GO:0065003
GO:0070062
GO:0070905
GO:1901135
GO:1904482
GO:1990830
HMNXSV003039652
Hs.8889.1.A2_3p_at
ILMN_1743784
ILMN_1811933
ILMN_2402463
L11931_at
PH_hs_0029657
TC17001201.hg
TC17002528.hg
g438633_3p_a_at
Participates
as a component of
Inferred To
SHM1 [cytosol] (Saccharomyces cerevisiae)
mel-32 [cytosol] (Caenorhabditis elegans)
shm2 [cytosol] (Schizosaccharomyces pombe)
shmt2 [cytosol] (Dictyostelium discoideum)
Homologues of PXLP-SHMT1 [cytosol] (Dictyostelium discoideum)
Homologues of PXLP-SHMT1 [cytosol] (Saccharomyces cerevisiae)
Homologues of PXLP-SHMT1 [cytosol] (Schizosaccharomyces pombe)
Shmt [cytosol] (Drosophila melanogaster)
Shmt1 [cytosol] (Mus musculus)
Shmt1 [cytosol] (Rattus norvegicus)
SHMT1 [cytosol] (Bos taurus)
SHMT1 [cytosol] (Gallus gallus)
SHMT1 [cytosol] (Sus scrofa)
PXLP-SHMT1 [cytosol] (Canis familiaris)
PXLP-SHMT1 [cytosol] (Danio rerio)
PXLP-SHMT1 [cytosol] (Schizosaccharomyces pombe)
SHM2 [cytosol] (Saccharomyces cerevisiae)
shmt1 [cytosol] (Dictyostelium discoideum)
shmt1 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
N6-pyridoxal phosphate-L-lysine at 257
Coordinate
257
PsiMod Name
N6-pyridoxal phosphate-L-lysine [MOD:00128]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.
Cross References
RefSeq
OpenTargets
IntEnz
HPA
GeneCards
Ensembl
ZINC target
PRO
Pharos - Targets
Orphanet
PDB
HMDB Protein
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P0DMM9 SULT1A3  1 0.556 3
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