PXLP-SHMT1 [cytosol]

Stable Identifier
R-HSA-71242
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SHMT1, serine hydroxymethyltransferase, glycine hydroxymethyltransferase, Serine methylase
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P34896 SHMT1
Gene Names
SHMT1
Chain
chain:1-483
Reference Genes
BioGPS Gene:6470 SHMT1
COSMIC (genes):SHMT1 SHMT1
CTD Gene:6470 SHMT1
dbSNP Gene:6470 SHMT1
ENSEMBL:ENSG00000176974 SHMT1
HGNC:10850 SHMT1
KEGG Gene (Homo sapiens):6470 SHMT1
Monarch:6470 SHMT1
NCBI Gene:6470 SHMT1
OMIM:182144 SHMT1
UCSC:P34896 SHMT1
Reference Transcript
Other Identifiers
0000380156
0000380341
00260+2.1.2.1
00460+2.1.2.1
00630+2.1.2.1
00670+2.1.2.1
00680+2.1.2.1
11733969_a_at
11740366_a_at
11751011_x_at
11756209_x_at
16842103
1BJ4
209980_s_at
224954_at
23314
2409444
2409446
2409449
2409450
34738_at
3748322
3748324
3748325
3748326
3748327
3748330
3748331
3748333
3748334
3748335
3748336
3748338
3748340
3748342
3748347
3748348
3748353
6470
6FL5
712_s_at
78803_at
8013243
A0A087WTD8
A_23_P502654
A_24_P205364
AAA36018
AAA36019
AAA36020
AAA63257
AAH07979
AAH22874
AAH38598
AC127537
AK298415
AL353997
BAG60641
BC007979
BC022874
BC038598
CAB54838
CAB54839
CAB54840
CCDS11196
CCDS11197
CCDS62112
CH471196
EAW55637
EAW55640
EAW55641
ENSG00000176974
ENSP00000318805
ENSP00000318868
ENSP00000345881
ENST00000316694
ENST00000316694.7
ENST00000352886
ENST00000352886.10
ENST00000354098
ENST00000354098.7
EntrezGene:6470
EntrezGene:SHMT1
g438633_3p_a_at
GE81357
GO:0000900
GO:0003674
GO:0003723
GO:0003729
GO:0003824
GO:0004372
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0006231
GO:0006412
GO:0006520
GO:0006544
GO:0006545
GO:0006563
GO:0006565
GO:0006730
GO:0008150
GO:0008270
GO:0008732
GO:0009056
GO:0009058
GO:0009113
GO:0016597
GO:0016740
GO:0016829
GO:0017148
GO:0019264
GO:0022607
GO:0030170
GO:0034641
GO:0035999
GO:0042802
GO:0042803
GO:0043167
GO:0043226
GO:0044281
GO:0045329
GO:0046653
GO:0046655
GO:0048027
GO:0050897
GO:0051186
GO:0051262
GO:0051289
GO:0065003
GO:0070062
GO:0070905
GO:1904482
GO:1990830
HGNC:10850
HPA023314
Hs.8889.1.A2_3p_at
ILMN_1743784
ILMN_1811933
ILMN_2402463
IPR001085
IPR015421
IPR015422
IPR015424
IPR019798
IPR039429
J3KRK5
J3KRZ5
L11931
L11931_at
L23928
MIM:182144
NM_001281786
NM_004169
NM_148918
NP_001268715
NP_004160
NP_683718
PF00464
PH_hs_0029657
SHMT1
SHMT1-201
SHMT1-202
SHMT1-203
TC17001201.hg
TC17002528.hg
UPI0000001C71
UPI000002AA9C
UPI00017A769A
XM_005256767
XM_011523992
XM_017024957
XM_017024958
XM_024450887
XM_024450888
XM_024450889
XM_024450890
XP_005256824
XP_011522294
XP_016880446
XP_016880447
XP_024306655
XP_024306656
XP_024306657
XP_024306658
Y14485
Y14486
Y14487
Participant Of
hasComponent
Inferred To
Homologues of PXLP-SHMT1 [cytosol] (Saccharomyces cerevisiae)
Homologues of PXLP-SHMT1 [cytosol] (Schizosaccharomyces pombe)
PXLP-SHMT1 [cytosol] (Bos taurus)
PXLP-SHMT1 [cytosol] (Caenorhabditis elegans)
PXLP-SHMT1 [cytosol] (Canis familiaris)
PXLP-SHMT1 [cytosol] (Danio rerio)
PXLP-SHMT1 [cytosol] (Drosophila melanogaster)
PXLP-SHMT1 [cytosol] (Gallus gallus)
PXLP-SHMT1 [cytosol] (Mus musculus)
PXLP-SHMT1 [cytosol] (Rattus norvegicus)
PXLP-SHMT1 [cytosol] (Saccharomyces cerevisiae)
PXLP-SHMT1 [cytosol] (Schizosaccharomyces pombe)
PXLP-SHMT1 [cytosol] (Sus scrofa)
PXLP-SHMT1 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
N6-pyridoxal phosphate-L-lysine at 257
Coordinate
257
PsiMod Name
N6-pyridoxal phosphate-L-lysine [MOD:00128]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.
Cross References
RefSeq
OpenTargets
IntEnz
GeneCards
ZINC target
PRO
Orphanet
HMDB Protein
PDB
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P0DMM9 SULT1A3  1 0.556 3