Trimethyllysine dioxygenase (TMLHE) dimer in the mitochondrial matrix catalyzes the reaction of oxygen, 2-oxoglutarate (2OG), and N6,N6,N6-trimethyl-L-lysine (TMLYS) to form CO2, 3-hydroxy-N6,N6,N6-trimethyl-L-lysine (HTMLYS), and succinate (SUCCA) (Vaz et al. 2001).
Back, JW, Vaz, FM, Westinga, K, Ofman, R
trimethyllysine dioxygenase activity of TMLHE:AscH-:Fe2+ dimer [mitochondrial matrix]
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