3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde

Stable Identifier
R-HSA-71218
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde
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Cytosolic 3-hydroxyanthranilate oxygenase catalyzes the reaction of 3-hydroxyanthranilate and O2 to form 2-amino-3-carboxymuconate semialdehyde.

Literature References
PubMed ID Title Journal Year
7514594 Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase.

Malherbe, P, Köhler, C, Da Prada, M, Lang, G, Kiefer, V, Schwarcz, R, Lahm, HW, Cesura, AM

J Biol Chem 1994
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
3-hydroxyanthranilate 3,4-dioxygenase activity of HAAO [cytosol]
Physical Entity
HAAO [cytosol]
Activity
3-hydroxyanthranilate 3,4-dioxygenase activity (0000334)
Orthologous Events
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Bos taurus)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Caenorhabditis elegans)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Canis familiaris)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Danio rerio)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Dictyostelium discoideum)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Gallus gallus)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Mus musculus)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Rattus norvegicus)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Saccharomyces cerevisiae)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Sus scrofa)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Xenopus tropicalis)
Authored
D'Eustachio, P  (2005-07-20)