3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde

Stable Identifier
R-HSA-71218
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic 3-hydroxyanthranilate oxygenase catalyzes the reaction of 3-hydroxyanthranilate and O2 to form 2-amino-3-carboxymuconate semialdehyde.

Literature References
PubMed ID Title Journal Year
7514594 Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase.

Lahm, HW, Cesura, AM, Kiefer, V, Schwarcz, R, Da Prada, M, Köhler, C, Lang, G, Malherbe, P

J Biol Chem 1994
Participants
Input
Output
Participates
as an event of
Catalyst Activity

3-hydroxyanthranilate 3,4-dioxygenase activity of HAAO [cytosol]

Physical Entity
HAAO [cytosol] (Homo sapiens)
Activity
3-hydroxyanthranilate 3,4-dioxygenase activity (GO:0000334)
Orthologous Events
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Bos taurus)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Caenorhabditis elegans)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Canis familiaris)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Danio rerio)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Dictyostelium discoideum)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Gallus gallus)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Mus musculus)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Rattus norvegicus)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Saccharomyces cerevisiae)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Sus scrofa)
3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Xenopus tropicalis)
Authored
D'Eustachio, P  (2005-07-20)
Cite Us!