Reactome | AASS [mitochondrial matrix]

AASS [mitochondrial matrix]

Stable Identifier

R-HSA-70924

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

lysine-ketoglutarate reductase /saccharopine dehydrogenase monomer, LKR/SDH

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UDR5 AASS

Gene Names

AASS

Chain

transit peptide:1-27, chain:28-926

Reference Genes

BioGPS Gene:10157 AASS

COSMIC (genes):AASS AASS

CTD Gene:10157 AASS

dbSNP Gene:10157 AASS

ENSEMBL:ENSG00000008311 AASS

ENSEMBL_homo_sapiens_GENE:ENSG00000008311.16 AASS

HGNC:17366 AASS

KEGG Gene (Homo sapiens):10157 AASS

Monarch:10157 AASS

NCBI Gene:10157 AASS

OMIM:605113 AASS

UCSC:Q9UDR5 AASS

Reference Transcript

RefSeq:NM_005763.3 AASS

Other Identifiers

10157

11739600_s_at

11739601_at

11750960_a_at

11755241_a_at

17062280

210852_PM_s_at

210852_s_at

214829_PM_at

214829_at

3070182

3070184

3070185

3070187

3070188

3070190

3070191

3070193

3070194

3070195

3070196

3070197

3070199

3070200

3070202

3070209

3070210

3070212

3070213

3070215

3070216

3070217

3070219

3070220

3070222

3070224

3070225

3070226

3070227

3070237

35870_at

66351_at

8142554

91550_r_at

A_23_P8754

GE559388

GE62673

GO:0000122

GO:0003714

GO:0003824

GO:0004753

GO:0004754

GO:0005634

GO:0005737

GO:0005739

GO:0005759

GO:0005829

GO:0006351

GO:0006355

GO:0006520

GO:0006554

GO:0006790

GO:0008152

GO:0016491

GO:0019477

GO:0019878

GO:0033512

GO:0042393

GO:0043226

GO:0043231

GO:0047130

GO:0047131

GO:0055086

GO:0140110

GO:1901135

HMNXSV003026737

HMNXSV003033938

Hs.323091.0.S1_3p_at

ILMN_1678323

ILMN_2157219

PH_hs_0025265

TC07001811.hg

g7264723_3p_s_at

Participates

as a component of

AASS tetramer [mitochondrial matrix] (Homo sapiens)

Inferred To

aass-1 [mitochondrial matrix] (Caenorhabditis elegans)

AASS [mitochondrial matrix] (Bos taurus)

AASS [mitochondrial matrix] (Canis familiaris)

AASS [mitochondrial matrix] (Danio rerio)

AASS [mitochondrial matrix] (Gallus gallus)

AASS [mitochondrial matrix] (Mus musculus)

AASS [mitochondrial matrix] (Rattus norvegicus)

AASS [mitochondrial matrix] (Saccharomyces cerevisiae)

AASS [mitochondrial matrix] (Schizosaccharomyces pombe)

AASS [mitochondrial matrix] (Sus scrofa)

LKRSDH [mitochondrial matrix] (Drosophila melanogaster)

aass [mitochondrial matrix] (Dictyostelium discoideum)

aass [mitochondrial matrix] (Xenopus tropicalis)

Cross References

RefSeq

NP_005754.2

OpenTargets

ENSG00000008311

HPA

ENSG00000008311-AASS

GeneCards

Q9UDR5

Ensembl

ENST00000679864, ENSG00000008311, ENST00000679511, ENSP00000377040, ENSP00000505958, ENST00000417368, ENSP00000505381, ENST00000393376, ENSP00000403768

PRO

Q9UDR5

Pharos - Targets

Q9UDR5

Orphanet

16442

HMDB Protein

HMDBP00852

PDB

8E8T, 5O1P, 5O1N, 5L76, 8E8U, 8E8V, 8DDA, 5L78, 5O1O

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.527	2

Cite Us!